SSH2-SLC6A4 Fusion FISH Probe
The SSH2-SLC6A4 Fusion FISH Probe is used to confirm a fusion of the SSH2 and SLC6A4 genes. The fusion of the SSH2 and SLC6A4 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SSH2-SLC6A4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SSH2-SLC6A4-20-RERE | 20 (40 μL) | 200 μL |
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| SSH2-SLC6A4-20-REOR | 20 (40 μL) | 200 μL |
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| SSH2-SLC6A4-20-REGO | 20 (40 μL) | 200 μL |
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| SSH2-SLC6A4-20-REGR | 20 (40 μL) | 200 μL |
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| SSH2-SLC6A4-20-REAQ | 20 (40 μL) | 200 μL |
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| SSH2-SLC6A4-20-ORRE | 20 (40 μL) | 200 μL |
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| SSH2-SLC6A4-20-OROR | 20 (40 μL) | 200 μL |
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| SSH2-SLC6A4-20-ORGO | 20 (40 μL) | 200 μL |
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| SSH2-SLC6A4-20-ORAQ | 20 (40 μL) | 200 μL |
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| SSH2-SLC6A4-20-GORE | 20 (40 μL) | 200 μL |
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| SSH2-SLC6A4-20-GOOR | 20 (40 μL) | 200 μL |
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| SSH2-SLC6A4-20-GOGO | 20 (40 μL) | 200 μL |
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| SSH2-SLC6A4-20-GOGR | 20 (40 μL) | 200 μL |
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| SSH2-SLC6A4-20-GOAQ | 20 (40 μL) | 200 μL |
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| SSH2-SLC6A4-20-GRRE | 20 (40 μL) | 200 μL |
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| SSH2-SLC6A4-20-GROR | 20 (40 μL) | 200 μL |
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| SSH2-SLC6A4-20-GRGO | 20 (40 μL) | 200 μL |
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| SSH2-SLC6A4-20-GRGR | 20 (40 μL) | 200 μL |
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| SSH2-SLC6A4-20-GRAQ | 20 (40 μL) | 200 μL |
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| SSH2-SLC6A4-20-AQRE | 20 (40 μL) | 200 μL |
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| SSH2-SLC6A4-20-AQOR | 20 (40 μL) | 200 μL |
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| SSH2-SLC6A4-20-AQGO | 20 (40 μL) | 200 μL |
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| SSH2-SLC6A4-20-AQGR | 20 (40 μL) | 200 μL |
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| SSH2-SLC6A4-20-AQAQ | 20 (40 μL) | 200 μL |
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SLC6A4 Gene Summary
This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq, Jul 2008]
Gene Name: Solute Carrier Family 6 Member 4
Chromosome: CHR17: 28523377 -28562954
Locus: 17q11.2
SSH2 Gene Summary
This gene encodes a protein tyrosine phosphatase that plays a key role in the regulation of actin filaments. The encoded protein dephosphorylates and activates cofilin, which promotes actin filament depolymerization. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Gene Name: Slingshot Protein Phosphatase 2
Chromosome: CHR17: 27952964 -28257018
Locus: 17q11.2
Gene Diseases
The SSH2 SLC6A4 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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