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SS18-SSX1 Fusion FISH Probe

The SS18-SSX1 Fusion FISH Probe is used to confirm a fusion of the SS18 and SSX1 genes. The fusion of the SS18 and SSX1 genes has been associated with Sarcoma, Sarcoma, and Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
SS18-SSX1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
SS18-SSX1-20-RERE 20 (40 μL) 200 μL
SS18-SSX1-20-REOR 20 (40 μL) 200 μL
SS18-SSX1-20-REGO 20 (40 μL) 200 μL
SS18-SSX1-20-REGR 20 (40 μL) 200 μL
SS18-SSX1-20-REAQ 20 (40 μL) 200 μL
SS18-SSX1-20-ORRE 20 (40 μL) 200 μL
SS18-SSX1-20-OROR 20 (40 μL) 200 μL
SS18-SSX1-20-ORGO 20 (40 μL) 200 μL
SS18-SSX1-20-ORAQ 20 (40 μL) 200 μL
SS18-SSX1-20-GORE 20 (40 μL) 200 μL
SS18-SSX1-20-GOOR 20 (40 μL) 200 μL
SS18-SSX1-20-GOGO 20 (40 μL) 200 μL
SS18-SSX1-20-GOGR 20 (40 μL) 200 μL
SS18-SSX1-20-GOAQ 20 (40 μL) 200 μL
SS18-SSX1-20-GRRE 20 (40 μL) 200 μL
SS18-SSX1-20-GROR 20 (40 μL) 200 μL
SS18-SSX1-20-GRGO 20 (40 μL) 200 μL
SS18-SSX1-20-GRGR 20 (40 μL) 200 μL
SS18-SSX1-20-GRAQ 20 (40 μL) 200 μL
SS18-SSX1-20-AQRE 20 (40 μL) 200 μL
SS18-SSX1-20-AQOR 20 (40 μL) 200 μL
SS18-SSX1-20-AQGO 20 (40 μL) 200 μL
SS18-SSX1-20-AQGR 20 (40 μL) 200 μL
SS18-SSX1-20-AQAQ 20 (40 μL) 200 μL

SSX1 Gene Summary

The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX2 and SSX4 family members, have been involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome X. [provided by RefSeq, Jul 2013]

Gene Name: SSX Family Member 1

Chromosome: CHRX: 48114796 -48126879

Locus: Xp11.23

SS18 Gene Summary

The SS18, NBAF Chromatin Remodeling Complex Subunit (SS18) gene is located on chr18 :23596216-23670611 at 18q11.2.

Gene Name: SS18, NBAF Chromatin Remodeling Complex Subunit

Chromosome: CHR18: 23596216 -23670611

Locus: 18q11.2

Gene Diseases

The SS18 SSX1 Fusion has been associated with the following diseases:

Disease Name
Sarcoma
Sarcoma
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.