SS18-DOCK2 Fusion FISH Probe
The SS18-DOCK2 Fusion FISH Probe is used to confirm a fusion of the SS18 and DOCK2 genes. The fusion of the SS18 and DOCK2 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SS18-DOCK2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SS18-DOCK2-20-RERE | 20 (40 μL) | 200 μL |
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| SS18-DOCK2-20-REOR | 20 (40 μL) | 200 μL |
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| SS18-DOCK2-20-REGO | 20 (40 μL) | 200 μL |
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| SS18-DOCK2-20-REGR | 20 (40 μL) | 200 μL |
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| SS18-DOCK2-20-REAQ | 20 (40 μL) | 200 μL |
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| SS18-DOCK2-20-ORRE | 20 (40 μL) | 200 μL |
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| SS18-DOCK2-20-OROR | 20 (40 μL) | 200 μL |
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| SS18-DOCK2-20-ORGO | 20 (40 μL) | 200 μL |
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| SS18-DOCK2-20-ORAQ | 20 (40 μL) | 200 μL |
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| SS18-DOCK2-20-GORE | 20 (40 μL) | 200 μL |
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| SS18-DOCK2-20-GOOR | 20 (40 μL) | 200 μL |
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| SS18-DOCK2-20-GOGO | 20 (40 μL) | 200 μL |
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| SS18-DOCK2-20-GOGR | 20 (40 μL) | 200 μL |
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| SS18-DOCK2-20-GOAQ | 20 (40 μL) | 200 μL |
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| SS18-DOCK2-20-GRRE | 20 (40 μL) | 200 μL |
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| SS18-DOCK2-20-GROR | 20 (40 μL) | 200 μL |
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| SS18-DOCK2-20-GRGO | 20 (40 μL) | 200 μL |
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| SS18-DOCK2-20-GRGR | 20 (40 μL) | 200 μL |
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| SS18-DOCK2-20-GRAQ | 20 (40 μL) | 200 μL |
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| SS18-DOCK2-20-AQRE | 20 (40 μL) | 200 μL |
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| SS18-DOCK2-20-AQOR | 20 (40 μL) | 200 μL |
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| SS18-DOCK2-20-AQGO | 20 (40 μL) | 200 μL |
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| SS18-DOCK2-20-AQGR | 20 (40 μL) | 200 μL |
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| SS18-DOCK2-20-AQAQ | 20 (40 μL) | 200 μL |
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DOCK2 Gene Summary
The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP. [provided by RefSeq, Oct 2016]
Gene Name: Dedicator Of Cytokinesis 2
Chromosome: CHR5: 169064250 -169510386
Locus: 5q35.1
SS18 Gene Summary
The SS18, NBAF Chromatin Remodeling Complex Subunit (SS18) gene is located on chr18 :23596216-23670611 at 18q11.2.
Gene Name: SS18, NBAF Chromatin Remodeling Complex Subunit
Chromosome: CHR18: 23596216 -23670611
Locus: 18q11.2
Gene Diseases
The SS18 DOCK2 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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