SRPK1-CCHCR1 Fusion FISH Probe
The SRPK1-CCHCR1 Fusion FISH Probe is used to confirm a fusion of the SRPK1 and CCHCR1 genes. The fusion of the SRPK1 and CCHCR1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SRPK1-CCHCR1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SRPK1-CCHCR1-20-RERE | 20 (40 μL) | 200 μL |
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| SRPK1-CCHCR1-20-REOR | 20 (40 μL) | 200 μL |
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| SRPK1-CCHCR1-20-REGO | 20 (40 μL) | 200 μL |
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| SRPK1-CCHCR1-20-REGR | 20 (40 μL) | 200 μL |
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| SRPK1-CCHCR1-20-REAQ | 20 (40 μL) | 200 μL |
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| SRPK1-CCHCR1-20-ORRE | 20 (40 μL) | 200 μL |
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| SRPK1-CCHCR1-20-OROR | 20 (40 μL) | 200 μL |
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| SRPK1-CCHCR1-20-ORGO | 20 (40 μL) | 200 μL |
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| SRPK1-CCHCR1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SRPK1-CCHCR1-20-GORE | 20 (40 μL) | 200 μL |
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| SRPK1-CCHCR1-20-GOOR | 20 (40 μL) | 200 μL |
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| SRPK1-CCHCR1-20-GOGO | 20 (40 μL) | 200 μL |
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| SRPK1-CCHCR1-20-GOGR | 20 (40 μL) | 200 μL |
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| SRPK1-CCHCR1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SRPK1-CCHCR1-20-GRRE | 20 (40 μL) | 200 μL |
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| SRPK1-CCHCR1-20-GROR | 20 (40 μL) | 200 μL |
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| SRPK1-CCHCR1-20-GRGO | 20 (40 μL) | 200 μL |
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| SRPK1-CCHCR1-20-GRGR | 20 (40 μL) | 200 μL |
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| SRPK1-CCHCR1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SRPK1-CCHCR1-20-AQRE | 20 (40 μL) | 200 μL |
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| SRPK1-CCHCR1-20-AQOR | 20 (40 μL) | 200 μL |
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| SRPK1-CCHCR1-20-AQGO | 20 (40 μL) | 200 μL |
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| SRPK1-CCHCR1-20-AQGR | 20 (40 μL) | 200 μL |
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| SRPK1-CCHCR1-20-AQAQ | 20 (40 μL) | 200 μL |
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SRPK1 Gene Summary
This gene encodes a serine/arginine protein kinase specific for the SR (serine/arginine-rich domain) family of splicing factors. The protein localizes to the nucleus and the cytoplasm. It is thought to play a role in regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors. Alternative splicing of this gene results in multiple transcript variants. Additional alternatively spliced transcript variants have been described for this gene, but their full length nature have not been determined.[provided by RefSeq, Jul 2010]
Gene Name: SRSF Protein Kinase 1
Chromosome: CHR6: 35800810 -35888957
Locus: 6p21.31
CCHCR1 Gene Summary
This gene encodes a protein with five coiled-coil alpha-helical rod domains that is thought to act as a regulator of mRNA metabolism through its interaction with mRNA-decapping protein 4. It localizes to P-bodies, the site of mRNA metabolism, with an N-terminus that is required for this subcellular localization, suggesting it is a P-body component. Naturally occurring mutations in this gene are associated with psoriasis. [provided by RefSeq, May 2017]
Gene Name: Coiled-coil Alpha-helical Rod Protein 1
Chromosome: CHR6_mcf_hap5: 2492151 -2507972
Locus: 6p21.33
Gene Diseases
The SRPK1 CCHCR1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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