SRGAP1-PWP1 Fusion FISH Probe
The SRGAP1-PWP1 Fusion FISH Probe is used to confirm a fusion of the SRGAP1 and PWP1 genes. The fusion of the SRGAP1 and PWP1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SRGAP1-PWP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SRGAP1-PWP1-20-RERE | 20 (40 μL) | 200 μL |
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| SRGAP1-PWP1-20-REOR | 20 (40 μL) | 200 μL |
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| SRGAP1-PWP1-20-REGO | 20 (40 μL) | 200 μL |
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| SRGAP1-PWP1-20-REGR | 20 (40 μL) | 200 μL |
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| SRGAP1-PWP1-20-REAQ | 20 (40 μL) | 200 μL |
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| SRGAP1-PWP1-20-ORRE | 20 (40 μL) | 200 μL |
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| SRGAP1-PWP1-20-OROR | 20 (40 μL) | 200 μL |
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| SRGAP1-PWP1-20-ORGO | 20 (40 μL) | 200 μL |
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| SRGAP1-PWP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SRGAP1-PWP1-20-GORE | 20 (40 μL) | 200 μL |
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| SRGAP1-PWP1-20-GOOR | 20 (40 μL) | 200 μL |
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| SRGAP1-PWP1-20-GOGO | 20 (40 μL) | 200 μL |
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| SRGAP1-PWP1-20-GOGR | 20 (40 μL) | 200 μL |
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| SRGAP1-PWP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SRGAP1-PWP1-20-GRRE | 20 (40 μL) | 200 μL |
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| SRGAP1-PWP1-20-GROR | 20 (40 μL) | 200 μL |
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| SRGAP1-PWP1-20-GRGO | 20 (40 μL) | 200 μL |
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| SRGAP1-PWP1-20-GRGR | 20 (40 μL) | 200 μL |
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| SRGAP1-PWP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SRGAP1-PWP1-20-AQRE | 20 (40 μL) | 200 μL |
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| SRGAP1-PWP1-20-AQOR | 20 (40 μL) | 200 μL |
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| SRGAP1-PWP1-20-AQGO | 20 (40 μL) | 200 μL |
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| SRGAP1-PWP1-20-AQGR | 20 (40 μL) | 200 μL |
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| SRGAP1-PWP1-20-AQAQ | 20 (40 μL) | 200 μL |
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PWP1 Gene Summary
The protein encoded by this gene contains several WD-40 repeats and is found mostly in the nucleus. The expression and localization of this protein are cell cycle dependent. Expression of this gene is upregulated in pancreatic adenocarcinoma. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
Gene Name: PWP1 Homolog, Endonuclein
Chromosome: CHR12: 108079589 -108106257
Locus: 12q23.3
SRGAP1 Gene Summary
The protein encoded by this gene is a GTPase activator, working with the GTPase CDC42 to negatively regulate neuronal migration. The encoded protein interacts with the transmembrane receptor ROBO1 to inactivate CDC42. [provided by RefSeq, Sep 2016]
Gene Name: SLIT-ROBO Rho GTPase Activating Protein 1
Chromosome: CHR12: 64238540 -64541613
Locus: 12q14.2
Gene Diseases
The SRGAP1 PWP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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