SREBF2-EFCAB6 Fusion FISH Probe
The SREBF2-EFCAB6 Fusion FISH Probe is used to confirm a fusion of the SREBF2 and EFCAB6 genes. The fusion of the SREBF2 and EFCAB6 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SREBF2-EFCAB6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SREBF2-EFCAB6-20-RERE | 20 (40 μL) | 200 μL |
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| SREBF2-EFCAB6-20-REOR | 20 (40 μL) | 200 μL |
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| SREBF2-EFCAB6-20-REGO | 20 (40 μL) | 200 μL |
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| SREBF2-EFCAB6-20-REGR | 20 (40 μL) | 200 μL |
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| SREBF2-EFCAB6-20-REAQ | 20 (40 μL) | 200 μL |
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| SREBF2-EFCAB6-20-ORRE | 20 (40 μL) | 200 μL |
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| SREBF2-EFCAB6-20-OROR | 20 (40 μL) | 200 μL |
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| SREBF2-EFCAB6-20-ORGO | 20 (40 μL) | 200 μL |
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| SREBF2-EFCAB6-20-ORAQ | 20 (40 μL) | 200 μL |
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| SREBF2-EFCAB6-20-GORE | 20 (40 μL) | 200 μL |
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| SREBF2-EFCAB6-20-GOOR | 20 (40 μL) | 200 μL |
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| SREBF2-EFCAB6-20-GOGO | 20 (40 μL) | 200 μL |
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| SREBF2-EFCAB6-20-GOGR | 20 (40 μL) | 200 μL |
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| SREBF2-EFCAB6-20-GOAQ | 20 (40 μL) | 200 μL |
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| SREBF2-EFCAB6-20-GRRE | 20 (40 μL) | 200 μL |
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| SREBF2-EFCAB6-20-GROR | 20 (40 μL) | 200 μL |
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| SREBF2-EFCAB6-20-GRGO | 20 (40 μL) | 200 μL |
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| SREBF2-EFCAB6-20-GRGR | 20 (40 μL) | 200 μL |
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| SREBF2-EFCAB6-20-GRAQ | 20 (40 μL) | 200 μL |
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| SREBF2-EFCAB6-20-AQRE | 20 (40 μL) | 200 μL |
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| SREBF2-EFCAB6-20-AQOR | 20 (40 μL) | 200 μL |
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| SREBF2-EFCAB6-20-AQGO | 20 (40 μL) | 200 μL |
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| SREBF2-EFCAB6-20-AQGR | 20 (40 μL) | 200 μL |
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| SREBF2-EFCAB6-20-AQAQ | 20 (40 μL) | 200 μL |
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SREBF2 Gene Summary
This gene encodes a member of the a ubiquitously expressed transcription factor that controls cholesterol homeostasis by regulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain and binds the sterol regulatory element 1 motif. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Name: Sterol Regulatory Element Binding Transcription Factor 2
Chromosome: CHR22: 42229105 -42302375
Locus: 22q13.2
EFCAB6 Gene Summary
This gene encodes a protein which directly binds the oncogene DJ-1 and androgen receptor to form a ternary complex in cells. This binding protein recruits histone-deacetylase complexes in order to repress transcription activity of androgen receptor. This protein may also play a role in spermatogenesis and fertilization. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Gene Name: EF-hand Calcium Binding Domain 6
Chromosome: CHR22: 43924623 -44208217
Locus: 22q13.2-q13.31
Gene Diseases
The SREBF2 EFCAB6 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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