SRCIN1-PCGF2 Fusion FISH Probe
The SRCIN1-PCGF2 Fusion FISH Probe is used to confirm a fusion of the SRCIN1 and PCGF2 genes. The fusion of the SRCIN1 and PCGF2 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SRCIN1-PCGF2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SRCIN1-PCGF2-20-RERE | 20 (40 μL) | 200 μL |
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| SRCIN1-PCGF2-20-REOR | 20 (40 μL) | 200 μL |
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| SRCIN1-PCGF2-20-REGO | 20 (40 μL) | 200 μL |
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| SRCIN1-PCGF2-20-REGR | 20 (40 μL) | 200 μL |
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| SRCIN1-PCGF2-20-REAQ | 20 (40 μL) | 200 μL |
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| SRCIN1-PCGF2-20-ORRE | 20 (40 μL) | 200 μL |
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| SRCIN1-PCGF2-20-OROR | 20 (40 μL) | 200 μL |
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| SRCIN1-PCGF2-20-ORGO | 20 (40 μL) | 200 μL |
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| SRCIN1-PCGF2-20-ORAQ | 20 (40 μL) | 200 μL |
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| SRCIN1-PCGF2-20-GORE | 20 (40 μL) | 200 μL |
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| SRCIN1-PCGF2-20-GOOR | 20 (40 μL) | 200 μL |
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| SRCIN1-PCGF2-20-GOGO | 20 (40 μL) | 200 μL |
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| SRCIN1-PCGF2-20-GOGR | 20 (40 μL) | 200 μL |
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| SRCIN1-PCGF2-20-GOAQ | 20 (40 μL) | 200 μL |
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| SRCIN1-PCGF2-20-GRRE | 20 (40 μL) | 200 μL |
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| SRCIN1-PCGF2-20-GROR | 20 (40 μL) | 200 μL |
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| SRCIN1-PCGF2-20-GRGO | 20 (40 μL) | 200 μL |
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| SRCIN1-PCGF2-20-GRGR | 20 (40 μL) | 200 μL |
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| SRCIN1-PCGF2-20-GRAQ | 20 (40 μL) | 200 μL |
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| SRCIN1-PCGF2-20-AQRE | 20 (40 μL) | 200 μL |
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| SRCIN1-PCGF2-20-AQOR | 20 (40 μL) | 200 μL |
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| SRCIN1-PCGF2-20-AQGO | 20 (40 μL) | 200 μL |
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| SRCIN1-PCGF2-20-AQGR | 20 (40 μL) | 200 μL |
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| SRCIN1-PCGF2-20-AQAQ | 20 (40 μL) | 200 μL |
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PCGF2 Gene Summary
The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses. [provided by RefSeq, Jul 2008]
Gene Name: Polycomb Group Ring Finger 2
Chromosome: CHR17: 36890149 -36904558
Locus: 17q12
SRCIN1 Gene Summary
The SRC Kinase Signaling Inhibitor 1 (SRCIN1) gene is located on chr17 :36686258-36762183 at 17q12.
Gene Name: SRC Kinase Signaling Inhibitor 1
Chromosome: CHR17: 36686258 -36762183
Locus: 17q12
Gene Diseases
The SRCIN1 PCGF2 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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