SQSTM1-AP1G2 Fusion FISH Probe
The SQSTM1-AP1G2 Fusion FISH Probe is used to confirm a fusion of the SQSTM1 and AP1G2 genes. The fusion of the SQSTM1 and AP1G2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SQSTM1-AP1G2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SQSTM1-AP1G2-20-RERE | 20 (40 μL) | 200 μL |
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| SQSTM1-AP1G2-20-REOR | 20 (40 μL) | 200 μL |
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| SQSTM1-AP1G2-20-REGO | 20 (40 μL) | 200 μL |
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| SQSTM1-AP1G2-20-REGR | 20 (40 μL) | 200 μL |
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| SQSTM1-AP1G2-20-REAQ | 20 (40 μL) | 200 μL |
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| SQSTM1-AP1G2-20-ORRE | 20 (40 μL) | 200 μL |
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| SQSTM1-AP1G2-20-OROR | 20 (40 μL) | 200 μL |
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| SQSTM1-AP1G2-20-ORGO | 20 (40 μL) | 200 μL |
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| SQSTM1-AP1G2-20-ORAQ | 20 (40 μL) | 200 μL |
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| SQSTM1-AP1G2-20-GORE | 20 (40 μL) | 200 μL |
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| SQSTM1-AP1G2-20-GOOR | 20 (40 μL) | 200 μL |
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| SQSTM1-AP1G2-20-GOGO | 20 (40 μL) | 200 μL |
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| SQSTM1-AP1G2-20-GOGR | 20 (40 μL) | 200 μL |
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| SQSTM1-AP1G2-20-GOAQ | 20 (40 μL) | 200 μL |
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| SQSTM1-AP1G2-20-GRRE | 20 (40 μL) | 200 μL |
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| SQSTM1-AP1G2-20-GROR | 20 (40 μL) | 200 μL |
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| SQSTM1-AP1G2-20-GRGO | 20 (40 μL) | 200 μL |
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| SQSTM1-AP1G2-20-GRGR | 20 (40 μL) | 200 μL |
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| SQSTM1-AP1G2-20-GRAQ | 20 (40 μL) | 200 μL |
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| SQSTM1-AP1G2-20-AQRE | 20 (40 μL) | 200 μL |
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| SQSTM1-AP1G2-20-AQOR | 20 (40 μL) | 200 μL |
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| SQSTM1-AP1G2-20-AQGO | 20 (40 μL) | 200 μL |
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| SQSTM1-AP1G2-20-AQGR | 20 (40 μL) | 200 μL |
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| SQSTM1-AP1G2-20-AQAQ | 20 (40 μL) | 200 μL |
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SQSTM1 Gene Summary
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq, Mar 2009]
Gene Name: Sequestosome 1
Chromosome: CHR5: 179233387 -179265077
Locus: 5q35.3
AP1G2 Gene Summary
Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. This protein along with the complex is thought to function at some trafficking step in the complex pathways between the trans-Golgi network and the cell surface. [provided by RefSeq, Aug 2017]
Gene Name: Adaptor Related Protein Complex 1 Gamma 2 Subunit
Chromosome: CHR14: 24028776 -24037279
Locus: 14q11.2
Gene Diseases
The SQSTM1 AP1G2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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