SPTAN1-MAPKAP1 Fusion FISH Probe
The SPTAN1-MAPKAP1 Fusion FISH Probe is used to confirm a fusion of the SPTAN1 and MAPKAP1 genes. The fusion of the SPTAN1 and MAPKAP1 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SPTAN1-MAPKAP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SPTAN1-MAPKAP1-20-RERE | 20 (40 μL) | 200 μL |
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| SPTAN1-MAPKAP1-20-REOR | 20 (40 μL) | 200 μL |
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| SPTAN1-MAPKAP1-20-REGO | 20 (40 μL) | 200 μL |
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| SPTAN1-MAPKAP1-20-REGR | 20 (40 μL) | 200 μL |
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| SPTAN1-MAPKAP1-20-REAQ | 20 (40 μL) | 200 μL |
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| SPTAN1-MAPKAP1-20-ORRE | 20 (40 μL) | 200 μL |
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| SPTAN1-MAPKAP1-20-OROR | 20 (40 μL) | 200 μL |
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| SPTAN1-MAPKAP1-20-ORGO | 20 (40 μL) | 200 μL |
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| SPTAN1-MAPKAP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SPTAN1-MAPKAP1-20-GORE | 20 (40 μL) | 200 μL |
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| SPTAN1-MAPKAP1-20-GOOR | 20 (40 μL) | 200 μL |
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| SPTAN1-MAPKAP1-20-GOGO | 20 (40 μL) | 200 μL |
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| SPTAN1-MAPKAP1-20-GOGR | 20 (40 μL) | 200 μL |
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| SPTAN1-MAPKAP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SPTAN1-MAPKAP1-20-GRRE | 20 (40 μL) | 200 μL |
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| SPTAN1-MAPKAP1-20-GROR | 20 (40 μL) | 200 μL |
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| SPTAN1-MAPKAP1-20-GRGO | 20 (40 μL) | 200 μL |
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| SPTAN1-MAPKAP1-20-GRGR | 20 (40 μL) | 200 μL |
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| SPTAN1-MAPKAP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SPTAN1-MAPKAP1-20-AQRE | 20 (40 μL) | 200 μL |
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| SPTAN1-MAPKAP1-20-AQOR | 20 (40 μL) | 200 μL |
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| SPTAN1-MAPKAP1-20-AQGO | 20 (40 μL) | 200 μL |
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| SPTAN1-MAPKAP1-20-AQGR | 20 (40 μL) | 200 μL |
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| SPTAN1-MAPKAP1-20-AQAQ | 20 (40 μL) | 200 μL |
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SPTAN1 Gene Summary
Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010]
Gene Name: Spectrin Alpha, Non-erythrocytic 1
Chromosome: CHR9: 131314836 -131395944
Locus: 9q34.11
MAPKAP1 Gene Summary
This gene encodes a protein that is highly similar to the yeast SIN1 protein, a stress-activated protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been described. Alternate polyadenylation sites as well as alternate 3' UTRs have been identified for transcripts of this gene. [provided by RefSeq, Jul 2008]
Gene Name: Mitogen-activated Protein Kinase Associated Protein 1
Chromosome: CHR9: 128199672 -128469513
Locus: 9q33.3
Gene Diseases
The SPTAN1 MAPKAP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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