SPRED1-TMCO5A Fusion FISH Probe
The SPRED1-TMCO5A Fusion FISH Probe is used to confirm a fusion of the SPRED1 and TMCO5A genes. The fusion of the SPRED1 and TMCO5A genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SPRED1-TMCO5A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SPRED1-TMCO5A-20-RERE | 20 (40 μL) | 200 μL |
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| SPRED1-TMCO5A-20-REOR | 20 (40 μL) | 200 μL |
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| SPRED1-TMCO5A-20-REGO | 20 (40 μL) | 200 μL |
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| SPRED1-TMCO5A-20-REGR | 20 (40 μL) | 200 μL |
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| SPRED1-TMCO5A-20-REAQ | 20 (40 μL) | 200 μL |
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| SPRED1-TMCO5A-20-ORRE | 20 (40 μL) | 200 μL |
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| SPRED1-TMCO5A-20-OROR | 20 (40 μL) | 200 μL |
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| SPRED1-TMCO5A-20-ORGO | 20 (40 μL) | 200 μL |
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| SPRED1-TMCO5A-20-ORAQ | 20 (40 μL) | 200 μL |
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| SPRED1-TMCO5A-20-GORE | 20 (40 μL) | 200 μL |
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| SPRED1-TMCO5A-20-GOOR | 20 (40 μL) | 200 μL |
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| SPRED1-TMCO5A-20-GOGO | 20 (40 μL) | 200 μL |
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| SPRED1-TMCO5A-20-GOGR | 20 (40 μL) | 200 μL |
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| SPRED1-TMCO5A-20-GOAQ | 20 (40 μL) | 200 μL |
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| SPRED1-TMCO5A-20-GRRE | 20 (40 μL) | 200 μL |
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| SPRED1-TMCO5A-20-GROR | 20 (40 μL) | 200 μL |
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| SPRED1-TMCO5A-20-GRGO | 20 (40 μL) | 200 μL |
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| SPRED1-TMCO5A-20-GRGR | 20 (40 μL) | 200 μL |
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| SPRED1-TMCO5A-20-GRAQ | 20 (40 μL) | 200 μL |
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| SPRED1-TMCO5A-20-AQRE | 20 (40 μL) | 200 μL |
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| SPRED1-TMCO5A-20-AQOR | 20 (40 μL) | 200 μL |
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| SPRED1-TMCO5A-20-AQGO | 20 (40 μL) | 200 μL |
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| SPRED1-TMCO5A-20-AQGR | 20 (40 μL) | 200 μL |
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| SPRED1-TMCO5A-20-AQAQ | 20 (40 μL) | 200 μL |
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TMCO5A Gene Summary
The Transmembrane And Coiled-coil Domains 5A (TMCO5A) gene is located on chr15 :38227456-38243623 at 15q14.
Gene Name: Transmembrane And Coiled-coil Domains 5A
Chromosome: CHR15: 38227456 -38243623
Locus: 15q14
SPRED1 Gene Summary
The protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS). [provided by RefSeq, Jul 2008]
Gene Name: Sprouty Related EVH1 Domain Containing 1
Chromosome: CHR15: 38545051 -38649450
Locus: 15q14
Gene Diseases
The SPRED1 TMCO5A Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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