SPON1-SIRT3 Fusion FISH Probe
The SPON1-SIRT3 Fusion FISH Probe is used to confirm a fusion of the SPON1 and SIRT3 genes. The fusion of the SPON1 and SIRT3 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SPON1-SIRT3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| SPON1-SIRT3-20-RERE | 20 (40 μL) | 200 μL |
|
|
| SPON1-SIRT3-20-REOR | 20 (40 μL) | 200 μL |
|
|
| SPON1-SIRT3-20-REGO | 20 (40 μL) | 200 μL |
|
|
| SPON1-SIRT3-20-REGR | 20 (40 μL) | 200 μL |
|
|
| SPON1-SIRT3-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| SPON1-SIRT3-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| SPON1-SIRT3-20-OROR | 20 (40 μL) | 200 μL |
|
|
| SPON1-SIRT3-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| SPON1-SIRT3-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| SPON1-SIRT3-20-GORE | 20 (40 μL) | 200 μL |
|
|
| SPON1-SIRT3-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| SPON1-SIRT3-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| SPON1-SIRT3-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| SPON1-SIRT3-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| SPON1-SIRT3-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| SPON1-SIRT3-20-GROR | 20 (40 μL) | 200 μL |
|
|
| SPON1-SIRT3-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| SPON1-SIRT3-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| SPON1-SIRT3-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| SPON1-SIRT3-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| SPON1-SIRT3-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| SPON1-SIRT3-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| SPON1-SIRT3-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| SPON1-SIRT3-20-AQAQ | 20 (40 μL) | 200 μL |
|
SPON1 Gene Summary
The Spondin 1 (SPON1) gene is located on chr11 :13984183-14289679 at 11p15.2.
Gene Name: Spondin 1
Chromosome: CHR11: 13984183 -14289679
Locus: 11p15.2
SIRT3 Gene Summary
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Sirtuin 3
Chromosome: CHR11: 215029 -236362
Locus: 11p15.5
Gene Diseases
The SPON1 SIRT3 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|