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SPINT2-MAP4K1 Fusion FISH Probe

The SPINT2-MAP4K1 Fusion FISH Probe is used to confirm a fusion of the SPINT2 and MAP4K1 genes. The fusion of the SPINT2 and MAP4K1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
SPINT2-MAP4K1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
SPINT2-MAP4K1-20-RERE 20 (40 μL) 200 μL
SPINT2-MAP4K1-20-REOR 20 (40 μL) 200 μL
SPINT2-MAP4K1-20-REGO 20 (40 μL) 200 μL
SPINT2-MAP4K1-20-REGR 20 (40 μL) 200 μL
SPINT2-MAP4K1-20-REAQ 20 (40 μL) 200 μL
SPINT2-MAP4K1-20-ORRE 20 (40 μL) 200 μL
SPINT2-MAP4K1-20-OROR 20 (40 μL) 200 μL
SPINT2-MAP4K1-20-ORGO 20 (40 μL) 200 μL
SPINT2-MAP4K1-20-ORAQ 20 (40 μL) 200 μL
SPINT2-MAP4K1-20-GORE 20 (40 μL) 200 μL
SPINT2-MAP4K1-20-GOOR 20 (40 μL) 200 μL
SPINT2-MAP4K1-20-GOGO 20 (40 μL) 200 μL
SPINT2-MAP4K1-20-GOGR 20 (40 μL) 200 μL
SPINT2-MAP4K1-20-GOAQ 20 (40 μL) 200 μL
SPINT2-MAP4K1-20-GRRE 20 (40 μL) 200 μL
SPINT2-MAP4K1-20-GROR 20 (40 μL) 200 μL
SPINT2-MAP4K1-20-GRGO 20 (40 μL) 200 μL
SPINT2-MAP4K1-20-GRGR 20 (40 μL) 200 μL
SPINT2-MAP4K1-20-GRAQ 20 (40 μL) 200 μL
SPINT2-MAP4K1-20-AQRE 20 (40 μL) 200 μL
SPINT2-MAP4K1-20-AQOR 20 (40 μL) 200 μL
SPINT2-MAP4K1-20-AQGO 20 (40 μL) 200 μL
SPINT2-MAP4K1-20-AQGR 20 (40 μL) 200 μL
SPINT2-MAP4K1-20-AQAQ 20 (40 μL) 200 μL

SPINT2 Gene Summary

This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

Gene Name: Serine Peptidase Inhibitor, Kunitz Type 2

Chromosome: CHR19: 38755097 -38783254

Locus: 19q13.2

MAP4K1 Gene Summary

The Mitogen-activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1) gene is located on chr19 :39078280-39108643 at 19q13.2.

Gene Name: Mitogen-activated Protein Kinase Kinase Kinase Kinase 1

Chromosome: CHR19: 39078280 -39108643

Locus: 19q13.2

Gene Diseases

The SPINT2 MAP4K1 Fusion has been associated with the following diseases:

Disease Name
Lung Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.