SPATA6-CRYZ Fusion FISH Probe
The SPATA6-CRYZ Fusion FISH Probe is used to confirm a fusion of the SPATA6 and CRYZ genes. The fusion of the SPATA6 and CRYZ genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SPATA6-CRYZ-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SPATA6-CRYZ-20-RERE | 20 (40 μL) | 200 μL |
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| SPATA6-CRYZ-20-REOR | 20 (40 μL) | 200 μL |
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| SPATA6-CRYZ-20-REGO | 20 (40 μL) | 200 μL |
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| SPATA6-CRYZ-20-REGR | 20 (40 μL) | 200 μL |
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| SPATA6-CRYZ-20-REAQ | 20 (40 μL) | 200 μL |
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| SPATA6-CRYZ-20-ORRE | 20 (40 μL) | 200 μL |
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| SPATA6-CRYZ-20-OROR | 20 (40 μL) | 200 μL |
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| SPATA6-CRYZ-20-ORGO | 20 (40 μL) | 200 μL |
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| SPATA6-CRYZ-20-ORAQ | 20 (40 μL) | 200 μL |
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| SPATA6-CRYZ-20-GORE | 20 (40 μL) | 200 μL |
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| SPATA6-CRYZ-20-GOOR | 20 (40 μL) | 200 μL |
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| SPATA6-CRYZ-20-GOGO | 20 (40 μL) | 200 μL |
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| SPATA6-CRYZ-20-GOGR | 20 (40 μL) | 200 μL |
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| SPATA6-CRYZ-20-GOAQ | 20 (40 μL) | 200 μL |
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| SPATA6-CRYZ-20-GRRE | 20 (40 μL) | 200 μL |
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| SPATA6-CRYZ-20-GROR | 20 (40 μL) | 200 μL |
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| SPATA6-CRYZ-20-GRGO | 20 (40 μL) | 200 μL |
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| SPATA6-CRYZ-20-GRGR | 20 (40 μL) | 200 μL |
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| SPATA6-CRYZ-20-GRAQ | 20 (40 μL) | 200 μL |
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| SPATA6-CRYZ-20-AQRE | 20 (40 μL) | 200 μL |
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| SPATA6-CRYZ-20-AQOR | 20 (40 μL) | 200 μL |
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| SPATA6-CRYZ-20-AQGO | 20 (40 μL) | 200 μL |
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| SPATA6-CRYZ-20-AQGR | 20 (40 μL) | 200 μL |
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| SPATA6-CRYZ-20-AQAQ | 20 (40 μL) | 200 μL |
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CRYZ Gene Summary
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One pseudogene is known to exist. [provided by RefSeq, Sep 2008]
Gene Name: Crystallin Zeta
Chromosome: CHR1: 75171171 -75199092
Locus: 1p31.1
SPATA6 Gene Summary
The Spermatogenesis Associated 6 (SPATA6) gene is located on chr1 :48761043-48937876 at 1p33.
Gene Name: Spermatogenesis Associated 6
Chromosome: CHR1: 48761043 -48937876
Locus: 1p33
Gene Diseases
The SPATA6 CRYZ Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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