SPATA5-MMRN1 Fusion FISH Probe
The SPATA5-MMRN1 Fusion FISH Probe is used to confirm a fusion of the SPATA5 and MMRN1 genes. The fusion of the SPATA5 and MMRN1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SPATA5-MMRN1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SPATA5-MMRN1-20-RERE | 20 (40 μL) | 200 μL |
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| SPATA5-MMRN1-20-REOR | 20 (40 μL) | 200 μL |
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| SPATA5-MMRN1-20-REGO | 20 (40 μL) | 200 μL |
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| SPATA5-MMRN1-20-REGR | 20 (40 μL) | 200 μL |
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| SPATA5-MMRN1-20-REAQ | 20 (40 μL) | 200 μL |
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| SPATA5-MMRN1-20-ORRE | 20 (40 μL) | 200 μL |
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| SPATA5-MMRN1-20-OROR | 20 (40 μL) | 200 μL |
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| SPATA5-MMRN1-20-ORGO | 20 (40 μL) | 200 μL |
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| SPATA5-MMRN1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SPATA5-MMRN1-20-GORE | 20 (40 μL) | 200 μL |
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| SPATA5-MMRN1-20-GOOR | 20 (40 μL) | 200 μL |
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| SPATA5-MMRN1-20-GOGO | 20 (40 μL) | 200 μL |
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| SPATA5-MMRN1-20-GOGR | 20 (40 μL) | 200 μL |
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| SPATA5-MMRN1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SPATA5-MMRN1-20-GRRE | 20 (40 μL) | 200 μL |
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| SPATA5-MMRN1-20-GROR | 20 (40 μL) | 200 μL |
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| SPATA5-MMRN1-20-GRGO | 20 (40 μL) | 200 μL |
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| SPATA5-MMRN1-20-GRGR | 20 (40 μL) | 200 μL |
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| SPATA5-MMRN1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SPATA5-MMRN1-20-AQRE | 20 (40 μL) | 200 μL |
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| SPATA5-MMRN1-20-AQOR | 20 (40 μL) | 200 μL |
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| SPATA5-MMRN1-20-AQGO | 20 (40 μL) | 200 μL |
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| SPATA5-MMRN1-20-AQGR | 20 (40 μL) | 200 μL |
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| SPATA5-MMRN1-20-AQAQ | 20 (40 μL) | 200 μL |
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MMRN1 Gene Summary
Multimerin is a massive, soluble protein found in platelets and in the endothelium of blood vessels. It is comprised of subunits linked by interchain disulfide bonds to form large, variably sized homomultimers. Multimerin is a factor V/Va-binding protein and may function as a carrier protein for platelet factor V. It may also have functions as an extracellular matrix or adhesive protein. Recently, patients with an unusual autosomal-dominant bleeding disorder (factor V Quebec) were found to have a deficiency of platelet multimerin. [provided by RefSeq, Jul 2008]
Gene Name: Multimerin 1
Chromosome: CHR4: 90816051 -90875780
Locus: 4q22.1
SPATA5 Gene Summary
This gene encodes a member of the ATPase associated with diverse activities family, whose members are defined by a highly conserved ATPase domain. Members of this family participate in diverse cellular processes that include membrane fusion, DNA replication, microtubule severing, and protein degradation. The protein encoded by this gene has a putative mitochondrial targeting sequence and has been proposed to function in maintenance of mitochondrial function and integrity during mouse spermatogenesis. Allelic variants in this gene have been associated with epilepsy, hearing loss, and cognitive disability syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
Gene Name: Spermatogenesis Associated 5
Chromosome: CHR4: 123844224 -124240604
Locus: 4q28.1
Gene Diseases
The SPATA5 MMRN1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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