SPAG9-TRIM37 Fusion FISH Probe
The SPAG9-TRIM37 Fusion FISH Probe is used to confirm a fusion of the SPAG9 and TRIM37 genes. The fusion of the SPAG9 and TRIM37 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SPAG9-TRIM37-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SPAG9-TRIM37-20-RERE | 20 (40 μL) | 200 μL |
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| SPAG9-TRIM37-20-REOR | 20 (40 μL) | 200 μL |
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| SPAG9-TRIM37-20-REGO | 20 (40 μL) | 200 μL |
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| SPAG9-TRIM37-20-REGR | 20 (40 μL) | 200 μL |
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| SPAG9-TRIM37-20-REAQ | 20 (40 μL) | 200 μL |
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| SPAG9-TRIM37-20-ORRE | 20 (40 μL) | 200 μL |
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| SPAG9-TRIM37-20-OROR | 20 (40 μL) | 200 μL |
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| SPAG9-TRIM37-20-ORGO | 20 (40 μL) | 200 μL |
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| SPAG9-TRIM37-20-ORAQ | 20 (40 μL) | 200 μL |
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| SPAG9-TRIM37-20-GORE | 20 (40 μL) | 200 μL |
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| SPAG9-TRIM37-20-GOOR | 20 (40 μL) | 200 μL |
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| SPAG9-TRIM37-20-GOGO | 20 (40 μL) | 200 μL |
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| SPAG9-TRIM37-20-GOGR | 20 (40 μL) | 200 μL |
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| SPAG9-TRIM37-20-GOAQ | 20 (40 μL) | 200 μL |
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| SPAG9-TRIM37-20-GRRE | 20 (40 μL) | 200 μL |
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| SPAG9-TRIM37-20-GROR | 20 (40 μL) | 200 μL |
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| SPAG9-TRIM37-20-GRGO | 20 (40 μL) | 200 μL |
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| SPAG9-TRIM37-20-GRGR | 20 (40 μL) | 200 μL |
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| SPAG9-TRIM37-20-GRAQ | 20 (40 μL) | 200 μL |
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| SPAG9-TRIM37-20-AQRE | 20 (40 μL) | 200 μL |
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| SPAG9-TRIM37-20-AQOR | 20 (40 μL) | 200 μL |
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| SPAG9-TRIM37-20-AQGO | 20 (40 μL) | 200 μL |
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| SPAG9-TRIM37-20-AQGR | 20 (40 μL) | 200 μL |
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| SPAG9-TRIM37-20-AQAQ | 20 (40 μL) | 200 μL |
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TRIM37 Gene Summary
This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. The gene mutations are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin. [provided by RefSeq, Mar 2016]
Gene Name: Tripartite Motif Containing 37
Chromosome: CHR17: 57059999 -57184266
Locus: 17q22
SPAG9 Gene Summary
This gene encodes a member of the cancer testis antigen gene family. The encoded protein functions as a scaffold protein that structurally organizes mitogen-activated protein kinases and mediates c-Jun-terminal kinase signaling. This protein also binds to kinesin-1 and may be involved in microtubule-based membrane transport. This protein may play a role in tumor growth and development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]
Gene Name: Sperm Associated Antigen 9
Chromosome: CHR17: 49039534 -49198226
Locus: 17q21.33
Gene Diseases
The SPAG9 TRIM37 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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