SPAG9-RDX Fusion FISH Probe
The SPAG9-RDX Fusion FISH Probe is used to confirm a fusion of the SPAG9 and RDX genes. The fusion of the SPAG9 and RDX genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SPAG9-RDX-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SPAG9-RDX-20-RERE | 20 (40 μL) | 200 μL |
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| SPAG9-RDX-20-REOR | 20 (40 μL) | 200 μL |
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| SPAG9-RDX-20-REGO | 20 (40 μL) | 200 μL |
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| SPAG9-RDX-20-REGR | 20 (40 μL) | 200 μL |
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| SPAG9-RDX-20-REAQ | 20 (40 μL) | 200 μL |
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| SPAG9-RDX-20-ORRE | 20 (40 μL) | 200 μL |
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| SPAG9-RDX-20-OROR | 20 (40 μL) | 200 μL |
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| SPAG9-RDX-20-ORGO | 20 (40 μL) | 200 μL |
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| SPAG9-RDX-20-ORAQ | 20 (40 μL) | 200 μL |
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| SPAG9-RDX-20-GORE | 20 (40 μL) | 200 μL |
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| SPAG9-RDX-20-GOOR | 20 (40 μL) | 200 μL |
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| SPAG9-RDX-20-GOGO | 20 (40 μL) | 200 μL |
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| SPAG9-RDX-20-GOGR | 20 (40 μL) | 200 μL |
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| SPAG9-RDX-20-GOAQ | 20 (40 μL) | 200 μL |
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| SPAG9-RDX-20-GRRE | 20 (40 μL) | 200 μL |
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| SPAG9-RDX-20-GROR | 20 (40 μL) | 200 μL |
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| SPAG9-RDX-20-GRGO | 20 (40 μL) | 200 μL |
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| SPAG9-RDX-20-GRGR | 20 (40 μL) | 200 μL |
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| SPAG9-RDX-20-GRAQ | 20 (40 μL) | 200 μL |
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| SPAG9-RDX-20-AQRE | 20 (40 μL) | 200 μL |
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| SPAG9-RDX-20-AQOR | 20 (40 μL) | 200 μL |
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| SPAG9-RDX-20-AQGO | 20 (40 μL) | 200 μL |
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| SPAG9-RDX-20-AQGR | 20 (40 μL) | 200 μL |
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| SPAG9-RDX-20-AQAQ | 20 (40 μL) | 200 μL |
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RDX Gene Summary
Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated version representing a pseudogene (RDXP2) was assigned to Xp21.3. Another pseudogene that seemed to lack introns (RDXP1) was mapped to 11p by Southern and PCR analyses. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
Gene Name: Radixin
Chromosome: CHR11: 110100165 -110167437
Locus: 11q22.3
SPAG9 Gene Summary
This gene encodes a member of the cancer testis antigen gene family. The encoded protein functions as a scaffold protein that structurally organizes mitogen-activated protein kinases and mediates c-Jun-terminal kinase signaling. This protein also binds to kinesin-1 and may be involved in microtubule-based membrane transport. This protein may play a role in tumor growth and development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]
Gene Name: Sperm Associated Antigen 9
Chromosome: CHR17: 49039534 -49198226
Locus: 17q21.33
Gene Diseases
The SPAG9 RDX Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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