SPAG9-PCMT1 Fusion FISH Probe
The SPAG9-PCMT1 Fusion FISH Probe is used to confirm a fusion of the SPAG9 and PCMT1 genes. The fusion of the SPAG9 and PCMT1 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SPAG9-PCMT1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| SPAG9-PCMT1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| SPAG9-PCMT1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| SPAG9-PCMT1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| SPAG9-PCMT1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| SPAG9-PCMT1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| SPAG9-PCMT1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| SPAG9-PCMT1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| SPAG9-PCMT1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| SPAG9-PCMT1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| SPAG9-PCMT1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| SPAG9-PCMT1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| SPAG9-PCMT1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| SPAG9-PCMT1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| SPAG9-PCMT1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| SPAG9-PCMT1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| SPAG9-PCMT1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| SPAG9-PCMT1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| SPAG9-PCMT1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| SPAG9-PCMT1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| SPAG9-PCMT1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| SPAG9-PCMT1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| SPAG9-PCMT1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| SPAG9-PCMT1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| SPAG9-PCMT1-20-AQAQ | 20 (40 μL) | 200 μL |
|
PCMT1 Gene Summary
This gene encodes a member of the type II class of protein carboxyl methyltransferase enzymes. The encoded enzyme plays a role in protein repair by recognizing and converting D-aspartyl and L-isoaspartyl residues resulting from spontaneous deamidation back to the normal L-aspartyl form. The encoded protein may play a protective role in the pathogenesis of Alzheimer's disease, and single nucleotide polymorphisms in this gene have been associated with spina bifida and premature ovarian failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
Gene Name: Protein-L-isoaspartate (D-aspartate) O-methyltransferase
Chromosome: CHR6: 150070830 -150132557
Locus: 6q25.1
SPAG9 Gene Summary
This gene encodes a member of the cancer testis antigen gene family. The encoded protein functions as a scaffold protein that structurally organizes mitogen-activated protein kinases and mediates c-Jun-terminal kinase signaling. This protein also binds to kinesin-1 and may be involved in microtubule-based membrane transport. This protein may play a role in tumor growth and development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]
Gene Name: Sperm Associated Antigen 9
Chromosome: CHR17: 49039534 -49198226
Locus: 17q21.33
Gene Diseases
The SPAG9 PCMT1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|