SPAG17-LRSAM1 Fusion FISH Probe
The SPAG17-LRSAM1 Fusion FISH Probe is used to confirm a fusion of the SPAG17 and LRSAM1 genes. The fusion of the SPAG17 and LRSAM1 genes has been associated with Mesothelioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SPAG17-LRSAM1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SPAG17-LRSAM1-20-RERE | 20 (40 μL) | 200 μL |
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| SPAG17-LRSAM1-20-REOR | 20 (40 μL) | 200 μL |
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| SPAG17-LRSAM1-20-REGO | 20 (40 μL) | 200 μL |
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| SPAG17-LRSAM1-20-REGR | 20 (40 μL) | 200 μL |
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| SPAG17-LRSAM1-20-REAQ | 20 (40 μL) | 200 μL |
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| SPAG17-LRSAM1-20-ORRE | 20 (40 μL) | 200 μL |
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| SPAG17-LRSAM1-20-OROR | 20 (40 μL) | 200 μL |
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| SPAG17-LRSAM1-20-ORGO | 20 (40 μL) | 200 μL |
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| SPAG17-LRSAM1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SPAG17-LRSAM1-20-GORE | 20 (40 μL) | 200 μL |
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| SPAG17-LRSAM1-20-GOOR | 20 (40 μL) | 200 μL |
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| SPAG17-LRSAM1-20-GOGO | 20 (40 μL) | 200 μL |
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| SPAG17-LRSAM1-20-GOGR | 20 (40 μL) | 200 μL |
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| SPAG17-LRSAM1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SPAG17-LRSAM1-20-GRRE | 20 (40 μL) | 200 μL |
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| SPAG17-LRSAM1-20-GROR | 20 (40 μL) | 200 μL |
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| SPAG17-LRSAM1-20-GRGO | 20 (40 μL) | 200 μL |
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| SPAG17-LRSAM1-20-GRGR | 20 (40 μL) | 200 μL |
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| SPAG17-LRSAM1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SPAG17-LRSAM1-20-AQRE | 20 (40 μL) | 200 μL |
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| SPAG17-LRSAM1-20-AQOR | 20 (40 μL) | 200 μL |
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| SPAG17-LRSAM1-20-AQGO | 20 (40 μL) | 200 μL |
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| SPAG17-LRSAM1-20-AQGR | 20 (40 μL) | 200 μL |
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| SPAG17-LRSAM1-20-AQAQ | 20 (40 μL) | 200 μL |
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LRSAM1 Gene Summary
This gene encodes a ring finger protein involved in a variety of functions, including regulation of signaling pathways and cell adhesion, mediation of self-ubiquitylation, and involvement in cargo sorting during receptor endocytosis. Mutations in this gene have been associated with Charcot-Marie-Tooth disease. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jan 2012]
Gene Name: Leucine Rich Repeat And Sterile Alpha Motif Containing 1
Chromosome: CHR9: 130213764 -130265780
Locus: 9q33.3-q34.11
SPAG17 Gene Summary
This gene encodes a central pair protein present in the axonemes of cells with a "9 + 2" organization of microtubules. The encoded protein is required for the proper function of the axoneme. Mutations in the orthologous gene in mice lead to primary ciliary dyskinesia characterized by immotile nasal and tracheal cilia, reduced clearance of nasal mucus, profound respiratory distress, hydrocephalus, and neonatal lethality within twelve hours of birth due to impaired airway mucociliary clearance. Single-nucleotide polymorphisms in this gene are associated with human height and targeted mutations lead to skeletal malformations affecting the limbs in mice, suggesting a role for this gene in skeletal development. [provided by RefSeq, Feb 2017]
Gene Name: Sperm Associated Antigen 17
Chromosome: CHR1: 118496287 -118727848
Locus: 1p12
Gene Diseases
The SPAG17 LRSAM1 Fusion has been associated with the following diseases:
| Disease Name |
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| Mesothelioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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