SP140L-PDE6D Fusion FISH Probe
The SP140L-PDE6D Fusion FISH Probe is used to confirm a fusion of the SP140L and PDE6D genes. The fusion of the SP140L and PDE6D genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SP140L-PDE6D-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SP140L-PDE6D-20-RERE | 20 (40 μL) | 200 μL |
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| SP140L-PDE6D-20-REOR | 20 (40 μL) | 200 μL |
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| SP140L-PDE6D-20-REGO | 20 (40 μL) | 200 μL |
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| SP140L-PDE6D-20-REGR | 20 (40 μL) | 200 μL |
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| SP140L-PDE6D-20-REAQ | 20 (40 μL) | 200 μL |
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| SP140L-PDE6D-20-ORRE | 20 (40 μL) | 200 μL |
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| SP140L-PDE6D-20-OROR | 20 (40 μL) | 200 μL |
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| SP140L-PDE6D-20-ORGO | 20 (40 μL) | 200 μL |
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| SP140L-PDE6D-20-ORAQ | 20 (40 μL) | 200 μL |
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| SP140L-PDE6D-20-GORE | 20 (40 μL) | 200 μL |
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| SP140L-PDE6D-20-GOOR | 20 (40 μL) | 200 μL |
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| SP140L-PDE6D-20-GOGO | 20 (40 μL) | 200 μL |
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| SP140L-PDE6D-20-GOGR | 20 (40 μL) | 200 μL |
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| SP140L-PDE6D-20-GOAQ | 20 (40 μL) | 200 μL |
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| SP140L-PDE6D-20-GRRE | 20 (40 μL) | 200 μL |
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| SP140L-PDE6D-20-GROR | 20 (40 μL) | 200 μL |
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| SP140L-PDE6D-20-GRGO | 20 (40 μL) | 200 μL |
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| SP140L-PDE6D-20-GRGR | 20 (40 μL) | 200 μL |
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| SP140L-PDE6D-20-GRAQ | 20 (40 μL) | 200 μL |
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| SP140L-PDE6D-20-AQRE | 20 (40 μL) | 200 μL |
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| SP140L-PDE6D-20-AQOR | 20 (40 μL) | 200 μL |
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| SP140L-PDE6D-20-AQGO | 20 (40 μL) | 200 μL |
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| SP140L-PDE6D-20-AQGR | 20 (40 μL) | 200 μL |
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| SP140L-PDE6D-20-AQAQ | 20 (40 μL) | 200 μL |
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PDE6D Gene Summary
This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE), a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE complex, the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants. [provided by RefSeq, Mar 2014]
Gene Name: Phosphodiesterase 6D
Chromosome: CHR2: 232597146 -232645974
Locus: 2q37.1
SP140L Gene Summary
The SP140 Nuclear Body Protein Like (SP140L) gene is located on chr2 :231191893-231268445 at 2q37.1.
Gene Name: SP140 Nuclear Body Protein Like
Chromosome: CHR2: 231191893 -231268445
Locus: 2q37.1
Gene Diseases
The SP140L PDE6D Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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