SP100-GIGYF2 Fusion FISH Probe
The SP100-GIGYF2 Fusion FISH Probe is used to confirm a fusion of the SP100 and GIGYF2 genes. The fusion of the SP100 and GIGYF2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SP100-GIGYF2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SP100-GIGYF2-20-RERE | 20 (40 μL) | 200 μL |
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| SP100-GIGYF2-20-REOR | 20 (40 μL) | 200 μL |
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| SP100-GIGYF2-20-REGO | 20 (40 μL) | 200 μL |
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| SP100-GIGYF2-20-REGR | 20 (40 μL) | 200 μL |
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| SP100-GIGYF2-20-REAQ | 20 (40 μL) | 200 μL |
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| SP100-GIGYF2-20-ORRE | 20 (40 μL) | 200 μL |
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| SP100-GIGYF2-20-OROR | 20 (40 μL) | 200 μL |
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| SP100-GIGYF2-20-ORGO | 20 (40 μL) | 200 μL |
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| SP100-GIGYF2-20-ORAQ | 20 (40 μL) | 200 μL |
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| SP100-GIGYF2-20-GORE | 20 (40 μL) | 200 μL |
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| SP100-GIGYF2-20-GOOR | 20 (40 μL) | 200 μL |
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| SP100-GIGYF2-20-GOGO | 20 (40 μL) | 200 μL |
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| SP100-GIGYF2-20-GOGR | 20 (40 μL) | 200 μL |
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| SP100-GIGYF2-20-GOAQ | 20 (40 μL) | 200 μL |
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| SP100-GIGYF2-20-GRRE | 20 (40 μL) | 200 μL |
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| SP100-GIGYF2-20-GROR | 20 (40 μL) | 200 μL |
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| SP100-GIGYF2-20-GRGO | 20 (40 μL) | 200 μL |
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| SP100-GIGYF2-20-GRGR | 20 (40 μL) | 200 μL |
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| SP100-GIGYF2-20-GRAQ | 20 (40 μL) | 200 μL |
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| SP100-GIGYF2-20-AQRE | 20 (40 μL) | 200 μL |
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| SP100-GIGYF2-20-AQOR | 20 (40 μL) | 200 μL |
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| SP100-GIGYF2-20-AQGO | 20 (40 μL) | 200 μL |
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| SP100-GIGYF2-20-AQGR | 20 (40 μL) | 200 μL |
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| SP100-GIGYF2-20-AQAQ | 20 (40 μL) | 200 μL |
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SP100 Gene Summary
This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein. [provided by RefSeq, Aug 2011]
Gene Name: SP100 Nuclear Antigen
Chromosome: CHR2: 231280870 -231410317
Locus: 2q37.1
GIGYF2 Gene Summary
This gene contains CAG trinucleotide repeats and encodes a protein containing several stretches of polyglutamine residues. The encoded protein may be involved in the regulation of tyrosine kinase receptor signaling. This gene is located in a chromosomal region that was genetically linked to Parkinson disease type 11, and mutations in this gene were thought to be causative for this disease. However, more recent studies in different populations have been unable to replicate this association. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
Gene Name: GRB10 Interacting GYF Protein 2
Chromosome: CHR2: 233562014 -233725289
Locus: 2q37.1
Gene Diseases
The SP100 GIGYF2 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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