SP1-WNT9B Fusion FISH Probe
The SP1-WNT9B Fusion FISH Probe is used to confirm a fusion of the SP1 and WNT9B genes. The fusion of the SP1 and WNT9B genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SP1-WNT9B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SP1-WNT9B-20-RERE | 20 (40 μL) | 200 μL |
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| SP1-WNT9B-20-REOR | 20 (40 μL) | 200 μL |
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| SP1-WNT9B-20-REGO | 20 (40 μL) | 200 μL |
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| SP1-WNT9B-20-REGR | 20 (40 μL) | 200 μL |
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| SP1-WNT9B-20-REAQ | 20 (40 μL) | 200 μL |
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| SP1-WNT9B-20-ORRE | 20 (40 μL) | 200 μL |
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| SP1-WNT9B-20-OROR | 20 (40 μL) | 200 μL |
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| SP1-WNT9B-20-ORGO | 20 (40 μL) | 200 μL |
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| SP1-WNT9B-20-ORAQ | 20 (40 μL) | 200 μL |
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| SP1-WNT9B-20-GORE | 20 (40 μL) | 200 μL |
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| SP1-WNT9B-20-GOOR | 20 (40 μL) | 200 μL |
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| SP1-WNT9B-20-GOGO | 20 (40 μL) | 200 μL |
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| SP1-WNT9B-20-GOGR | 20 (40 μL) | 200 μL |
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| SP1-WNT9B-20-GOAQ | 20 (40 μL) | 200 μL |
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| SP1-WNT9B-20-GRRE | 20 (40 μL) | 200 μL |
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| SP1-WNT9B-20-GROR | 20 (40 μL) | 200 μL |
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| SP1-WNT9B-20-GRGO | 20 (40 μL) | 200 μL |
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| SP1-WNT9B-20-GRGR | 20 (40 μL) | 200 μL |
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| SP1-WNT9B-20-GRAQ | 20 (40 μL) | 200 μL |
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| SP1-WNT9B-20-AQRE | 20 (40 μL) | 200 μL |
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| SP1-WNT9B-20-AQOR | 20 (40 μL) | 200 μL |
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| SP1-WNT9B-20-AQGO | 20 (40 μL) | 200 μL |
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| SP1-WNT9B-20-AQGR | 20 (40 μL) | 200 μL |
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| SP1-WNT9B-20-AQAQ | 20 (40 μL) | 200 μL |
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SP1 Gene Summary
The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]
Gene Name: Sp1 Transcription Factor
Chromosome: CHR12: 53773978 -53810226
Locus: 12q13.13
WNT9B Gene Summary
The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. Study of its expression in the teratocarcinoma cell line NT2 suggests that it may be implicated in the early process of neuronal differentiation of NT2 cells induced by retinoic acid. This gene is clustered with WNT3, another family member, in the chromosome 17q21 region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Gene Name: Wnt Family Member 9B
Chromosome: CHR17: 44928967 -44954437
Locus: 17q21.32
Gene Diseases
The SP1 WNT9B Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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