SOX5-SPSB2 Fusion FISH Probe
The SOX5-SPSB2 Fusion FISH Probe is used to confirm a fusion of the SOX5 and SPSB2 genes. The fusion of the SOX5 and SPSB2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SOX5-SPSB2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SOX5-SPSB2-20-RERE | 20 (40 μL) | 200 μL |
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| SOX5-SPSB2-20-REOR | 20 (40 μL) | 200 μL |
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| SOX5-SPSB2-20-REGO | 20 (40 μL) | 200 μL |
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| SOX5-SPSB2-20-REGR | 20 (40 μL) | 200 μL |
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| SOX5-SPSB2-20-REAQ | 20 (40 μL) | 200 μL |
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| SOX5-SPSB2-20-ORRE | 20 (40 μL) | 200 μL |
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| SOX5-SPSB2-20-OROR | 20 (40 μL) | 200 μL |
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| SOX5-SPSB2-20-ORGO | 20 (40 μL) | 200 μL |
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| SOX5-SPSB2-20-ORAQ | 20 (40 μL) | 200 μL |
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| SOX5-SPSB2-20-GORE | 20 (40 μL) | 200 μL |
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| SOX5-SPSB2-20-GOOR | 20 (40 μL) | 200 μL |
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| SOX5-SPSB2-20-GOGO | 20 (40 μL) | 200 μL |
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| SOX5-SPSB2-20-GOGR | 20 (40 μL) | 200 μL |
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| SOX5-SPSB2-20-GOAQ | 20 (40 μL) | 200 μL |
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| SOX5-SPSB2-20-GRRE | 20 (40 μL) | 200 μL |
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| SOX5-SPSB2-20-GROR | 20 (40 μL) | 200 μL |
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| SOX5-SPSB2-20-GRGO | 20 (40 μL) | 200 μL |
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| SOX5-SPSB2-20-GRGR | 20 (40 μL) | 200 μL |
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| SOX5-SPSB2-20-GRAQ | 20 (40 μL) | 200 μL |
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| SOX5-SPSB2-20-AQRE | 20 (40 μL) | 200 μL |
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| SOX5-SPSB2-20-AQOR | 20 (40 μL) | 200 μL |
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| SOX5-SPSB2-20-AQGO | 20 (40 μL) | 200 μL |
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| SOX5-SPSB2-20-AQGR | 20 (40 μL) | 200 μL |
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| SOX5-SPSB2-20-AQAQ | 20 (40 μL) | 200 μL |
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SOX5 Gene Summary
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The encoded protein may play a role in chondrogenesis. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Name: SRY-box 5
Chromosome: CHR12: 23685230 -24715380
Locus: 12p12.1
SPSB2 Gene Summary
This gene encodes a member of a subfamily of proteins containing a central SPRY (repeats in splA and RyR) domain and a C-terminal suppressor of cytokine signaling (SOCS) box. This protein plays a role in cell signaling. This gene is present in a gene-rich cluster on chromosome 12p13 in the vicinity of the CD4 antigen and triosephosphate isomerase genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Gene Name: SplA/ryanodine Receptor Domain And SOCS Box Containing 2
Chromosome: CHR12: 6980099 -6982521
Locus: 12p13.31
Gene Diseases
The SOX5 SPSB2 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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