SOS1-DTL Fusion FISH Probe
The SOS1-DTL Fusion FISH Probe is used to confirm a fusion of the SOS1 and DTL genes. The fusion of the SOS1 and DTL genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SOS1-DTL-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SOS1-DTL-20-RERE | 20 (40 μL) | 200 μL |
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| SOS1-DTL-20-REOR | 20 (40 μL) | 200 μL |
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| SOS1-DTL-20-REGO | 20 (40 μL) | 200 μL |
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| SOS1-DTL-20-REGR | 20 (40 μL) | 200 μL |
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| SOS1-DTL-20-REAQ | 20 (40 μL) | 200 μL |
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| SOS1-DTL-20-ORRE | 20 (40 μL) | 200 μL |
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| SOS1-DTL-20-OROR | 20 (40 μL) | 200 μL |
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| SOS1-DTL-20-ORGO | 20 (40 μL) | 200 μL |
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| SOS1-DTL-20-ORAQ | 20 (40 μL) | 200 μL |
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| SOS1-DTL-20-GORE | 20 (40 μL) | 200 μL |
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| SOS1-DTL-20-GOOR | 20 (40 μL) | 200 μL |
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| SOS1-DTL-20-GOGO | 20 (40 μL) | 200 μL |
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| SOS1-DTL-20-GOGR | 20 (40 μL) | 200 μL |
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| SOS1-DTL-20-GOAQ | 20 (40 μL) | 200 μL |
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| SOS1-DTL-20-GRRE | 20 (40 μL) | 200 μL |
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| SOS1-DTL-20-GROR | 20 (40 μL) | 200 μL |
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| SOS1-DTL-20-GRGO | 20 (40 μL) | 200 μL |
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| SOS1-DTL-20-GRGR | 20 (40 μL) | 200 μL |
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| SOS1-DTL-20-GRAQ | 20 (40 μL) | 200 μL |
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| SOS1-DTL-20-AQRE | 20 (40 μL) | 200 μL |
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| SOS1-DTL-20-AQOR | 20 (40 μL) | 200 μL |
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| SOS1-DTL-20-AQGO | 20 (40 μL) | 200 μL |
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| SOS1-DTL-20-AQGR | 20 (40 μL) | 200 μL |
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| SOS1-DTL-20-AQAQ | 20 (40 μL) | 200 μL |
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SOS1 Gene Summary
This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq, Jul 2008]
Gene Name: SOS Ras/Rac Guanine Nucleotide Exchange Factor 1
Chromosome: CHR2: 39208689 -39347604
Locus: 2p22.1
DTL Gene Summary
The Denticleless E3 Ubiquitin Protein Ligase Homolog (DTL) gene is located on chr1 :212208918-212278187 at 1q32.3.
Gene Name: Denticleless E3 Ubiquitin Protein Ligase Homolog
Chromosome: CHR1: 212208918 -212278187
Locus: 1q32.3
Gene Diseases
The SOS1 DTL Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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