SORL1-CEP164 Fusion FISH Probe
The SORL1-CEP164 Fusion FISH Probe is used to confirm a fusion of the SORL1 and CEP164 genes. The fusion of the SORL1 and CEP164 genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SORL1-CEP164-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SORL1-CEP164-20-RERE | 20 (40 μL) | 200 μL |
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| SORL1-CEP164-20-REOR | 20 (40 μL) | 200 μL |
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| SORL1-CEP164-20-REGO | 20 (40 μL) | 200 μL |
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| SORL1-CEP164-20-REGR | 20 (40 μL) | 200 μL |
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| SORL1-CEP164-20-REAQ | 20 (40 μL) | 200 μL |
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| SORL1-CEP164-20-ORRE | 20 (40 μL) | 200 μL |
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| SORL1-CEP164-20-OROR | 20 (40 μL) | 200 μL |
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| SORL1-CEP164-20-ORGO | 20 (40 μL) | 200 μL |
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| SORL1-CEP164-20-ORAQ | 20 (40 μL) | 200 μL |
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| SORL1-CEP164-20-GORE | 20 (40 μL) | 200 μL |
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| SORL1-CEP164-20-GOOR | 20 (40 μL) | 200 μL |
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| SORL1-CEP164-20-GOGO | 20 (40 μL) | 200 μL |
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| SORL1-CEP164-20-GOGR | 20 (40 μL) | 200 μL |
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| SORL1-CEP164-20-GOAQ | 20 (40 μL) | 200 μL |
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| SORL1-CEP164-20-GRRE | 20 (40 μL) | 200 μL |
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| SORL1-CEP164-20-GROR | 20 (40 μL) | 200 μL |
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| SORL1-CEP164-20-GRGO | 20 (40 μL) | 200 μL |
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| SORL1-CEP164-20-GRGR | 20 (40 μL) | 200 μL |
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| SORL1-CEP164-20-GRAQ | 20 (40 μL) | 200 μL |
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| SORL1-CEP164-20-AQRE | 20 (40 μL) | 200 μL |
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| SORL1-CEP164-20-AQOR | 20 (40 μL) | 200 μL |
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| SORL1-CEP164-20-AQGO | 20 (40 μL) | 200 μL |
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| SORL1-CEP164-20-AQGR | 20 (40 μL) | 200 μL |
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| SORL1-CEP164-20-AQAQ | 20 (40 μL) | 200 μL |
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SORL1 Gene Summary
This gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 (VPS10) domain-containing receptor family, and the low density lipoprotein receptor (LDLR) family. The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat. The encoded preproprotein is proteolytically processed to generate the mature receptor, which likely plays roles in endocytosis and sorting. Mutations in this gene may be associated with Alzheimer's disease. [provided by RefSeq, Feb 2016]
Gene Name: Sortilin Related Receptor 1
Chromosome: CHR11: 121322911 -121504471
Locus: 11q24.1
CEP164 Gene Summary
This gene encodes a centrosomal protein involved in microtubule organization, DNA damage response, and chromosome segregation. The encoded protein is required for assembly of primary cilia and localizes to mature centrioles. Defects in this gene are a cause of nephronophthisis-related ciliopathies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
Gene Name: Centrosomal Protein 164
Chromosome: CHR11: 117198570 -117283982
Locus: 11q23.3
Gene Diseases
The SORL1 CEP164 Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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