SON-IL10RB Fusion FISH Probe
The SON-IL10RB Fusion FISH Probe is used to confirm a fusion of the SON and IL10RB genes. The fusion of the SON and IL10RB genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SON-IL10RB-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SON-IL10RB-20-RERE | 20 (40 μL) | 200 μL |
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| SON-IL10RB-20-REOR | 20 (40 μL) | 200 μL |
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| SON-IL10RB-20-REGO | 20 (40 μL) | 200 μL |
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| SON-IL10RB-20-REGR | 20 (40 μL) | 200 μL |
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| SON-IL10RB-20-REAQ | 20 (40 μL) | 200 μL |
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| SON-IL10RB-20-ORRE | 20 (40 μL) | 200 μL |
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| SON-IL10RB-20-OROR | 20 (40 μL) | 200 μL |
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| SON-IL10RB-20-ORGO | 20 (40 μL) | 200 μL |
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| SON-IL10RB-20-ORAQ | 20 (40 μL) | 200 μL |
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| SON-IL10RB-20-GORE | 20 (40 μL) | 200 μL |
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| SON-IL10RB-20-GOOR | 20 (40 μL) | 200 μL |
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| SON-IL10RB-20-GOGO | 20 (40 μL) | 200 μL |
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| SON-IL10RB-20-GOGR | 20 (40 μL) | 200 μL |
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| SON-IL10RB-20-GOAQ | 20 (40 μL) | 200 μL |
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| SON-IL10RB-20-GRRE | 20 (40 μL) | 200 μL |
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| SON-IL10RB-20-GROR | 20 (40 μL) | 200 μL |
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| SON-IL10RB-20-GRGO | 20 (40 μL) | 200 μL |
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| SON-IL10RB-20-GRGR | 20 (40 μL) | 200 μL |
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| SON-IL10RB-20-GRAQ | 20 (40 μL) | 200 μL |
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| SON-IL10RB-20-AQRE | 20 (40 μL) | 200 μL |
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| SON-IL10RB-20-AQOR | 20 (40 μL) | 200 μL |
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| SON-IL10RB-20-AQGO | 20 (40 μL) | 200 μL |
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| SON-IL10RB-20-AQGR | 20 (40 μL) | 200 μL |
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| SON-IL10RB-20-AQAQ | 20 (40 μL) | 200 μL |
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IL10RB Gene Summary
The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21. [provided by RefSeq, Jul 2008]
Gene Name: Interleukin 10 Receptor Subunit Beta
Chromosome: CHR21: 34638671 -34669520
Locus: 21q22.11
SON Gene Summary
This gene encodes a protein that contains multiple simple repeats. The encoded protein binds RNA and promotes pre-mRNA splicing, particularly of transcripts with poor splice sites. The protein also recognizes a specific DNA sequence found in the human hepatitis B virus (HBV) and represses HBV core promoter activity. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Name: SON DNA Binding Protein
Chromosome: CHR21: 34915349 -34949812
Locus: 21q22.11
Gene Diseases
The SON IL10RB Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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