SOCS6-CTDP1 Fusion FISH Probe
The SOCS6-CTDP1 Fusion FISH Probe is used to confirm a fusion of the SOCS6 and CTDP1 genes. The fusion of the SOCS6 and CTDP1 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SOCS6-CTDP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SOCS6-CTDP1-20-RERE | 20 (40 μL) | 200 μL |
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| SOCS6-CTDP1-20-REOR | 20 (40 μL) | 200 μL |
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| SOCS6-CTDP1-20-REGO | 20 (40 μL) | 200 μL |
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| SOCS6-CTDP1-20-REGR | 20 (40 μL) | 200 μL |
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| SOCS6-CTDP1-20-REAQ | 20 (40 μL) | 200 μL |
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| SOCS6-CTDP1-20-ORRE | 20 (40 μL) | 200 μL |
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| SOCS6-CTDP1-20-OROR | 20 (40 μL) | 200 μL |
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| SOCS6-CTDP1-20-ORGO | 20 (40 μL) | 200 μL |
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| SOCS6-CTDP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SOCS6-CTDP1-20-GORE | 20 (40 μL) | 200 μL |
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| SOCS6-CTDP1-20-GOOR | 20 (40 μL) | 200 μL |
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| SOCS6-CTDP1-20-GOGO | 20 (40 μL) | 200 μL |
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| SOCS6-CTDP1-20-GOGR | 20 (40 μL) | 200 μL |
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| SOCS6-CTDP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SOCS6-CTDP1-20-GRRE | 20 (40 μL) | 200 μL |
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| SOCS6-CTDP1-20-GROR | 20 (40 μL) | 200 μL |
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| SOCS6-CTDP1-20-GRGO | 20 (40 μL) | 200 μL |
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| SOCS6-CTDP1-20-GRGR | 20 (40 μL) | 200 μL |
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| SOCS6-CTDP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SOCS6-CTDP1-20-AQRE | 20 (40 μL) | 200 μL |
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| SOCS6-CTDP1-20-AQOR | 20 (40 μL) | 200 μL |
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| SOCS6-CTDP1-20-AQGO | 20 (40 μL) | 200 μL |
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| SOCS6-CTDP1-20-AQGR | 20 (40 μL) | 200 μL |
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| SOCS6-CTDP1-20-AQAQ | 20 (40 μL) | 200 μL |
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CTDP1 Gene Summary
This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF, and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II), making it available for initiation of gene expression. Mutations in this gene are associated with congenital cataracts, facial dysmorphism and neuropathy syndrome (CCFDN). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
Gene Name: CTD Phosphatase Subunit 1
Chromosome: CHR18: 77439800 -77514510
Locus: 18q23
SOCS6 Gene Summary
The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines. [provided by RefSeq, Jul 2008]
Gene Name: Suppressor Of Cytokine Signaling 6
Chromosome: CHR18: 67956136 -67997434
Locus: 18q22.2
Gene Diseases
The SOCS6 CTDP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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