SNX6-MIPOL1 Fusion FISH Probe
The SNX6-MIPOL1 Fusion FISH Probe is used to confirm a fusion of the SNX6 and MIPOL1 genes. The fusion of the SNX6 and MIPOL1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SNX6-MIPOL1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SNX6-MIPOL1-20-RERE | 20 (40 μL) | 200 μL |
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| SNX6-MIPOL1-20-REOR | 20 (40 μL) | 200 μL |
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| SNX6-MIPOL1-20-REGO | 20 (40 μL) | 200 μL |
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| SNX6-MIPOL1-20-REGR | 20 (40 μL) | 200 μL |
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| SNX6-MIPOL1-20-REAQ | 20 (40 μL) | 200 μL |
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| SNX6-MIPOL1-20-ORRE | 20 (40 μL) | 200 μL |
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| SNX6-MIPOL1-20-OROR | 20 (40 μL) | 200 μL |
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| SNX6-MIPOL1-20-ORGO | 20 (40 μL) | 200 μL |
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| SNX6-MIPOL1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SNX6-MIPOL1-20-GORE | 20 (40 μL) | 200 μL |
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| SNX6-MIPOL1-20-GOOR | 20 (40 μL) | 200 μL |
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| SNX6-MIPOL1-20-GOGO | 20 (40 μL) | 200 μL |
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| SNX6-MIPOL1-20-GOGR | 20 (40 μL) | 200 μL |
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| SNX6-MIPOL1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SNX6-MIPOL1-20-GRRE | 20 (40 μL) | 200 μL |
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| SNX6-MIPOL1-20-GROR | 20 (40 μL) | 200 μL |
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| SNX6-MIPOL1-20-GRGO | 20 (40 μL) | 200 μL |
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| SNX6-MIPOL1-20-GRGR | 20 (40 μL) | 200 μL |
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| SNX6-MIPOL1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SNX6-MIPOL1-20-AQRE | 20 (40 μL) | 200 μL |
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| SNX6-MIPOL1-20-AQOR | 20 (40 μL) | 200 μL |
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| SNX6-MIPOL1-20-AQGO | 20 (40 μL) | 200 μL |
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| SNX6-MIPOL1-20-AQGR | 20 (40 μL) | 200 μL |
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| SNX6-MIPOL1-20-AQAQ | 20 (40 μL) | 200 μL |
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SNX6 Gene Summary
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associates with the long isoform of the leptin receptor, the transforming growth factor-beta family of receptor serine-threonine kinases, and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor. This protein may form oligomeric complexes with family member proteins through interactions of both the PX domain and the coiled coil regions of the molecules. Translocation of this protein from the cytoplasm to the nucleus occurs after binding to proviral integration site 1 protein. This gene results in two transcripts encoding two distinct isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Sorting Nexin 6
Chromosome: CHR14: 35030617 -35099366
Locus: 14q13.1
MIPOL1 Gene Summary
This gene encodes a coiled-coil domain-containing protein. The encoded protein may function as a tumor suppressor. A translocation that results in truncation of the protein encoded by this locus has been associated with mirror-image polydactyly, also known as Laurin-Sandrow Syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2010]
Gene Name: Mirror-image Polydactyly 1
Chromosome: CHR14: 37667117 -38020464
Locus: 14q13.3-q21.1
Gene Diseases
The SNX6 MIPOL1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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