SNX30-ALDOB Fusion FISH Probe
The SNX30-ALDOB Fusion FISH Probe is used to confirm a fusion of the SNX30 and ALDOB genes. The fusion of the SNX30 and ALDOB genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SNX30-ALDOB-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SNX30-ALDOB-20-RERE | 20 (40 μL) | 200 μL |
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| SNX30-ALDOB-20-REOR | 20 (40 μL) | 200 μL |
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| SNX30-ALDOB-20-REGO | 20 (40 μL) | 200 μL |
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| SNX30-ALDOB-20-REGR | 20 (40 μL) | 200 μL |
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| SNX30-ALDOB-20-REAQ | 20 (40 μL) | 200 μL |
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| SNX30-ALDOB-20-ORRE | 20 (40 μL) | 200 μL |
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| SNX30-ALDOB-20-OROR | 20 (40 μL) | 200 μL |
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| SNX30-ALDOB-20-ORGO | 20 (40 μL) | 200 μL |
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| SNX30-ALDOB-20-ORAQ | 20 (40 μL) | 200 μL |
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| SNX30-ALDOB-20-GORE | 20 (40 μL) | 200 μL |
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| SNX30-ALDOB-20-GOOR | 20 (40 μL) | 200 μL |
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| SNX30-ALDOB-20-GOGO | 20 (40 μL) | 200 μL |
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| SNX30-ALDOB-20-GOGR | 20 (40 μL) | 200 μL |
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| SNX30-ALDOB-20-GOAQ | 20 (40 μL) | 200 μL |
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| SNX30-ALDOB-20-GRRE | 20 (40 μL) | 200 μL |
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| SNX30-ALDOB-20-GROR | 20 (40 μL) | 200 μL |
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| SNX30-ALDOB-20-GRGO | 20 (40 μL) | 200 μL |
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| SNX30-ALDOB-20-GRGR | 20 (40 μL) | 200 μL |
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| SNX30-ALDOB-20-GRAQ | 20 (40 μL) | 200 μL |
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| SNX30-ALDOB-20-AQRE | 20 (40 μL) | 200 μL |
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| SNX30-ALDOB-20-AQOR | 20 (40 μL) | 200 μL |
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| SNX30-ALDOB-20-AQGO | 20 (40 μL) | 200 μL |
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| SNX30-ALDOB-20-AQGR | 20 (40 μL) | 200 μL |
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| SNX30-ALDOB-20-AQAQ | 20 (40 μL) | 200 μL |
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ALDOB Gene Summary
Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. [provided by RefSeq, Dec 2008]
Gene Name: Aldolase, Fructose-bisphosphate B
Chromosome: CHR9: 104182841 -104198062
Locus: 9q31.1
SNX30 Gene Summary
The Sorting Nexin Family Member 30 (SNX30) gene is located on chr9 :115513133-115637267 at 9q32.
Gene Name: Sorting Nexin Family Member 30
Chromosome: CHR9: 115513133 -115637267
Locus: 9q32
Gene Diseases
The SNX30 ALDOB Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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