SNX11-MED24 Fusion FISH Probe
The SNX11-MED24 Fusion FISH Probe is used to confirm a fusion of the SNX11 and MED24 genes. The fusion of the SNX11 and MED24 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SNX11-MED24-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SNX11-MED24-20-RERE | 20 (40 μL) | 200 μL |
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| SNX11-MED24-20-REOR | 20 (40 μL) | 200 μL |
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| SNX11-MED24-20-REGO | 20 (40 μL) | 200 μL |
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| SNX11-MED24-20-REGR | 20 (40 μL) | 200 μL |
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| SNX11-MED24-20-REAQ | 20 (40 μL) | 200 μL |
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| SNX11-MED24-20-ORRE | 20 (40 μL) | 200 μL |
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| SNX11-MED24-20-OROR | 20 (40 μL) | 200 μL |
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| SNX11-MED24-20-ORGO | 20 (40 μL) | 200 μL |
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| SNX11-MED24-20-ORAQ | 20 (40 μL) | 200 μL |
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| SNX11-MED24-20-GORE | 20 (40 μL) | 200 μL |
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| SNX11-MED24-20-GOOR | 20 (40 μL) | 200 μL |
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| SNX11-MED24-20-GOGO | 20 (40 μL) | 200 μL |
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| SNX11-MED24-20-GOGR | 20 (40 μL) | 200 μL |
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| SNX11-MED24-20-GOAQ | 20 (40 μL) | 200 μL |
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| SNX11-MED24-20-GRRE | 20 (40 μL) | 200 μL |
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| SNX11-MED24-20-GROR | 20 (40 μL) | 200 μL |
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| SNX11-MED24-20-GRGO | 20 (40 μL) | 200 μL |
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| SNX11-MED24-20-GRGR | 20 (40 μL) | 200 μL |
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| SNX11-MED24-20-GRAQ | 20 (40 μL) | 200 μL |
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| SNX11-MED24-20-AQRE | 20 (40 μL) | 200 μL |
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| SNX11-MED24-20-AQOR | 20 (40 μL) | 200 μL |
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| SNX11-MED24-20-AQGO | 20 (40 μL) | 200 μL |
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| SNX11-MED24-20-AQGR | 20 (40 μL) | 200 μL |
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| SNX11-MED24-20-AQAQ | 20 (40 μL) | 200 μL |
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MED24 Gene Summary
This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Mediator Complex Subunit 24
Chromosome: CHR17: 38175349 -38210889
Locus: 17q21.1
SNX11 Gene Summary
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. This gene encodes a protein of unknown function. This gene results in two transcript variants differing in the 5' UTR, but encoding the same protein. [provided by RefSeq, Jul 2008]
Gene Name: Sorting Nexin 11
Chromosome: CHR17: 46184919 -46200105
Locus: 17q21.32
Gene Diseases
The SNX11 MED24 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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