SNX1-SCG5 Fusion FISH Probe
The SNX1-SCG5 Fusion FISH Probe is used to confirm a fusion of the SNX1 and SCG5 genes. The fusion of the SNX1 and SCG5 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SNX1-SCG5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SNX1-SCG5-20-RERE | 20 (40 μL) | 200 μL |
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| SNX1-SCG5-20-REOR | 20 (40 μL) | 200 μL |
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| SNX1-SCG5-20-REGO | 20 (40 μL) | 200 μL |
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| SNX1-SCG5-20-REGR | 20 (40 μL) | 200 μL |
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| SNX1-SCG5-20-REAQ | 20 (40 μL) | 200 μL |
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| SNX1-SCG5-20-ORRE | 20 (40 μL) | 200 μL |
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| SNX1-SCG5-20-OROR | 20 (40 μL) | 200 μL |
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| SNX1-SCG5-20-ORGO | 20 (40 μL) | 200 μL |
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| SNX1-SCG5-20-ORAQ | 20 (40 μL) | 200 μL |
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| SNX1-SCG5-20-GORE | 20 (40 μL) | 200 μL |
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| SNX1-SCG5-20-GOOR | 20 (40 μL) | 200 μL |
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| SNX1-SCG5-20-GOGO | 20 (40 μL) | 200 μL |
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| SNX1-SCG5-20-GOGR | 20 (40 μL) | 200 μL |
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| SNX1-SCG5-20-GOAQ | 20 (40 μL) | 200 μL |
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| SNX1-SCG5-20-GRRE | 20 (40 μL) | 200 μL |
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| SNX1-SCG5-20-GROR | 20 (40 μL) | 200 μL |
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| SNX1-SCG5-20-GRGO | 20 (40 μL) | 200 μL |
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| SNX1-SCG5-20-GRGR | 20 (40 μL) | 200 μL |
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| SNX1-SCG5-20-GRAQ | 20 (40 μL) | 200 μL |
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| SNX1-SCG5-20-AQRE | 20 (40 μL) | 200 μL |
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| SNX1-SCG5-20-AQOR | 20 (40 μL) | 200 μL |
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| SNX1-SCG5-20-AQGO | 20 (40 μL) | 200 μL |
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| SNX1-SCG5-20-AQGR | 20 (40 μL) | 200 μL |
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| SNX1-SCG5-20-AQAQ | 20 (40 μL) | 200 μL |
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SCG5 Gene Summary
This gene encodes a secreted chaperone protein that prevents the aggregation of other secreted proteins, including proteins that are associated with neurodegenerative and metabolic disease. The encoded protein may be best known for its role in the trafficking and activation of prohormone convertase PC2 (encoded by Gene ID: 5126). Phosphorylation of the encoded protein has been shown to have an inhibitory effect on its chaperone function. [provided by RefSeq, Jul 2016]
Gene Name: Secretogranin V
Chromosome: CHR15: 32933869 -32989298
Locus: 15q13.3
SNX1 Gene Summary
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Sorting Nexin 1
Chromosome: CHR15: 64388082 -64436433
Locus: 15q22.31
Gene Diseases
The SNX1 SCG5 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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