SNTG2-RBKS Fusion FISH Probe
The SNTG2-RBKS Fusion FISH Probe is used to confirm a fusion of the SNTG2 and RBKS genes. The fusion of the SNTG2 and RBKS genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SNTG2-RBKS-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SNTG2-RBKS-20-RERE | 20 (40 μL) | 200 μL |
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| SNTG2-RBKS-20-REOR | 20 (40 μL) | 200 μL |
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| SNTG2-RBKS-20-REGO | 20 (40 μL) | 200 μL |
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| SNTG2-RBKS-20-REGR | 20 (40 μL) | 200 μL |
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| SNTG2-RBKS-20-REAQ | 20 (40 μL) | 200 μL |
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| SNTG2-RBKS-20-ORRE | 20 (40 μL) | 200 μL |
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| SNTG2-RBKS-20-OROR | 20 (40 μL) | 200 μL |
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| SNTG2-RBKS-20-ORGO | 20 (40 μL) | 200 μL |
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| SNTG2-RBKS-20-ORAQ | 20 (40 μL) | 200 μL |
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| SNTG2-RBKS-20-GORE | 20 (40 μL) | 200 μL |
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| SNTG2-RBKS-20-GOOR | 20 (40 μL) | 200 μL |
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| SNTG2-RBKS-20-GOGO | 20 (40 μL) | 200 μL |
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| SNTG2-RBKS-20-GOGR | 20 (40 μL) | 200 μL |
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| SNTG2-RBKS-20-GOAQ | 20 (40 μL) | 200 μL |
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| SNTG2-RBKS-20-GRRE | 20 (40 μL) | 200 μL |
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| SNTG2-RBKS-20-GROR | 20 (40 μL) | 200 μL |
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| SNTG2-RBKS-20-GRGO | 20 (40 μL) | 200 μL |
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| SNTG2-RBKS-20-GRGR | 20 (40 μL) | 200 μL |
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| SNTG2-RBKS-20-GRAQ | 20 (40 μL) | 200 μL |
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| SNTG2-RBKS-20-AQRE | 20 (40 μL) | 200 μL |
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| SNTG2-RBKS-20-AQOR | 20 (40 μL) | 200 μL |
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| SNTG2-RBKS-20-AQGO | 20 (40 μL) | 200 μL |
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| SNTG2-RBKS-20-AQGR | 20 (40 μL) | 200 μL |
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| SNTG2-RBKS-20-AQAQ | 20 (40 μL) | 200 μL |
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SNTG2 Gene Summary
This gene encodes a protein belonging to the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that bind to components of mechanosenstive sodium channels and the extreme carboxy-terminal domain of dystrophin and dystrophin-related proteins. The PDZ domain of this protein product interacts with a protein component of a mechanosensitive sodium channel that affects channel gating. Absence or reduction of this protein product has been associated with Duchenne muscular dystrophy. There is evidence of alternative splicing yet the full-length nature of these variants has not been described. [provided by RefSeq, Jul 2008]
Gene Name: Syntrophin Gamma 2
Chromosome: CHR2: 946553 -1371384
Locus: 2p25.3
RBKS Gene Summary
This gene encodes a member of the carbohydrate kinase PfkB family. The encoded protein phosphorylates ribose to form ribose-5-phosphate in the presence of ATP and magnesium as a first step in ribose metabolism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Gene Name: Ribokinase
Chromosome: CHR2: 28004265 -28113223
Locus: 2p23.2
Gene Diseases
The SNTG2 RBKS Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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