SNTB1-COL22A1 Fusion FISH Probe
The SNTB1-COL22A1 Fusion FISH Probe is used to confirm a fusion of the SNTB1 and COL22A1 genes. The fusion of the SNTB1 and COL22A1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SNTB1-COL22A1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SNTB1-COL22A1-20-RERE | 20 (40 μL) | 200 μL |
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| SNTB1-COL22A1-20-REOR | 20 (40 μL) | 200 μL |
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| SNTB1-COL22A1-20-REGO | 20 (40 μL) | 200 μL |
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| SNTB1-COL22A1-20-REGR | 20 (40 μL) | 200 μL |
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| SNTB1-COL22A1-20-REAQ | 20 (40 μL) | 200 μL |
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| SNTB1-COL22A1-20-ORRE | 20 (40 μL) | 200 μL |
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| SNTB1-COL22A1-20-OROR | 20 (40 μL) | 200 μL |
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| SNTB1-COL22A1-20-ORGO | 20 (40 μL) | 200 μL |
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| SNTB1-COL22A1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SNTB1-COL22A1-20-GORE | 20 (40 μL) | 200 μL |
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| SNTB1-COL22A1-20-GOOR | 20 (40 μL) | 200 μL |
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| SNTB1-COL22A1-20-GOGO | 20 (40 μL) | 200 μL |
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| SNTB1-COL22A1-20-GOGR | 20 (40 μL) | 200 μL |
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| SNTB1-COL22A1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SNTB1-COL22A1-20-GRRE | 20 (40 μL) | 200 μL |
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| SNTB1-COL22A1-20-GROR | 20 (40 μL) | 200 μL |
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| SNTB1-COL22A1-20-GRGO | 20 (40 μL) | 200 μL |
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| SNTB1-COL22A1-20-GRGR | 20 (40 μL) | 200 μL |
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| SNTB1-COL22A1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SNTB1-COL22A1-20-AQRE | 20 (40 μL) | 200 μL |
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| SNTB1-COL22A1-20-AQOR | 20 (40 μL) | 200 μL |
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| SNTB1-COL22A1-20-AQGO | 20 (40 μL) | 200 μL |
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| SNTB1-COL22A1-20-AQGR | 20 (40 μL) | 200 μL |
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| SNTB1-COL22A1-20-AQAQ | 20 (40 μL) | 200 μL |
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SNTB1 Gene Summary
Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes. [provided by RefSeq, Jul 2008]
Gene Name: Syntrophin Beta 1
Chromosome: CHR8: 121547984 -121824309
Locus: 8q24.12
COL22A1 Gene Summary
This gene encodes member of the collagen family which is thought to contribute to the stabilization of myotendinous junctions and strengthen skeletal muscle attachments during contractile activity. It belongs to the fibril-associated collagens with interrupted triple helix (FACIT) subset of the collagen superfamily, which associate with collagen fibers through their C-terminal collagenous domains and mediate protein-protein interactions through their N-terminal noncollagenous domains. The encoded protein is deposited in the basement membrane zone of the myotendinous junction which is present only at the tissue junctions of muscles, tendons, the heart, articular cartilage, and skin. A knockdown of the orthologous zebrafish gene induces a muscular dystrophy by disruption of the myotendinous junction. [provided by RefSeq, May 2017]
Gene Name: Collagen Type XXII Alpha 1 Chain
Chromosome: CHR8: 139600477 -139926236
Locus: 8q24.23-q24.3
Gene Diseases
The SNTB1 COL22A1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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