SNRNP70-CDC42EP5 Fusion FISH Probe
The SNRNP70-CDC42EP5 Fusion FISH Probe is used to confirm a fusion of the SNRNP70 and CDC42EP5 genes. The fusion of the SNRNP70 and CDC42EP5 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SNRNP70-CDC42EP5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SNRNP70-CDC42EP5-20-RERE | 20 (40 μL) | 200 μL |
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| SNRNP70-CDC42EP5-20-REOR | 20 (40 μL) | 200 μL |
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| SNRNP70-CDC42EP5-20-REGO | 20 (40 μL) | 200 μL |
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| SNRNP70-CDC42EP5-20-REGR | 20 (40 μL) | 200 μL |
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| SNRNP70-CDC42EP5-20-REAQ | 20 (40 μL) | 200 μL |
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| SNRNP70-CDC42EP5-20-ORRE | 20 (40 μL) | 200 μL |
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| SNRNP70-CDC42EP5-20-OROR | 20 (40 μL) | 200 μL |
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| SNRNP70-CDC42EP5-20-ORGO | 20 (40 μL) | 200 μL |
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| SNRNP70-CDC42EP5-20-ORAQ | 20 (40 μL) | 200 μL |
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| SNRNP70-CDC42EP5-20-GORE | 20 (40 μL) | 200 μL |
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| SNRNP70-CDC42EP5-20-GOOR | 20 (40 μL) | 200 μL |
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| SNRNP70-CDC42EP5-20-GOGO | 20 (40 μL) | 200 μL |
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| SNRNP70-CDC42EP5-20-GOGR | 20 (40 μL) | 200 μL |
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| SNRNP70-CDC42EP5-20-GOAQ | 20 (40 μL) | 200 μL |
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| SNRNP70-CDC42EP5-20-GRRE | 20 (40 μL) | 200 μL |
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| SNRNP70-CDC42EP5-20-GROR | 20 (40 μL) | 200 μL |
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| SNRNP70-CDC42EP5-20-GRGO | 20 (40 μL) | 200 μL |
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| SNRNP70-CDC42EP5-20-GRGR | 20 (40 μL) | 200 μL |
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| SNRNP70-CDC42EP5-20-GRAQ | 20 (40 μL) | 200 μL |
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| SNRNP70-CDC42EP5-20-AQRE | 20 (40 μL) | 200 μL |
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| SNRNP70-CDC42EP5-20-AQOR | 20 (40 μL) | 200 μL |
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| SNRNP70-CDC42EP5-20-AQGO | 20 (40 μL) | 200 μL |
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| SNRNP70-CDC42EP5-20-AQGR | 20 (40 μL) | 200 μL |
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| SNRNP70-CDC42EP5-20-AQAQ | 20 (40 μL) | 200 μL |
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SNRNP70 Gene Summary
The Small Nuclear Ribonucleoprotein U1 Subunit 70 (SNRNP70) gene is located on chr19 :49588464-49611870 at 19q13.33.
Gene Name: Small Nuclear Ribonucleoprotein U1 Subunit 70
Chromosome: CHR19: 49588464 -49611870
Locus: 19q13.33
CDC42EP5 Gene Summary
Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts [provided by RefSeq, Jul 2013]
Gene Name: CDC42 Effector Protein 5
Chromosome: CHR19: 54976209 -54984422
Locus: 19q13.42
Gene Diseases
The SNRNP70 CDC42EP5 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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