SNAP29-IGLL1 Fusion FISH Probe
The SNAP29-IGLL1 Fusion FISH Probe is used to confirm a fusion of the SNAP29 and IGLL1 genes. The fusion of the SNAP29 and IGLL1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SNAP29-IGLL1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| SNAP29-IGLL1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| SNAP29-IGLL1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| SNAP29-IGLL1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| SNAP29-IGLL1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| SNAP29-IGLL1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| SNAP29-IGLL1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| SNAP29-IGLL1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| SNAP29-IGLL1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| SNAP29-IGLL1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| SNAP29-IGLL1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| SNAP29-IGLL1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| SNAP29-IGLL1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| SNAP29-IGLL1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| SNAP29-IGLL1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| SNAP29-IGLL1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| SNAP29-IGLL1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| SNAP29-IGLL1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| SNAP29-IGLL1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| SNAP29-IGLL1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| SNAP29-IGLL1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| SNAP29-IGLL1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| SNAP29-IGLL1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| SNAP29-IGLL1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| SNAP29-IGLL1-20-AQAQ | 20 (40 μL) | 200 μL |
|
IGLL1 Gene Summary
The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Immunoglobulin Lambda Like Polypeptide 1
Chromosome: CHR22: 23915312 -23922495
Locus: 22q11.23
SNAP29 Gene Summary
This gene, a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps. Two other members of this gene family, SNAP23 and SNAP25, encode proteins that bind a syntaxin protein and mediate synaptic vesicle membrane docking and fusion to the plasma membrane. The protein encoded by this gene binds tightly to multiple syntaxins and is localized to intracellular membrane structures rather than to the plasma membrane. While the protein is mostly membrane-bound, a significant fraction of it is found free in the cytoplasm. Use of multiple polyadenylation sites has been noted for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Synaptosome Associated Protein 29
Chromosome: CHR22: 21213291 -21245501
Locus: 22q11.21
Gene Diseases
The SNAP29 IGLL1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|