SMYD3-EDARADD Fusion FISH Probe
The SMYD3-EDARADD Fusion FISH Probe is used to confirm a fusion of the SMYD3 and EDARADD genes. The fusion of the SMYD3 and EDARADD genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SMYD3-EDARADD-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SMYD3-EDARADD-20-RERE | 20 (40 μL) | 200 μL |
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| SMYD3-EDARADD-20-REOR | 20 (40 μL) | 200 μL |
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| SMYD3-EDARADD-20-REGO | 20 (40 μL) | 200 μL |
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| SMYD3-EDARADD-20-REGR | 20 (40 μL) | 200 μL |
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| SMYD3-EDARADD-20-REAQ | 20 (40 μL) | 200 μL |
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| SMYD3-EDARADD-20-ORRE | 20 (40 μL) | 200 μL |
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| SMYD3-EDARADD-20-OROR | 20 (40 μL) | 200 μL |
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| SMYD3-EDARADD-20-ORGO | 20 (40 μL) | 200 μL |
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| SMYD3-EDARADD-20-ORAQ | 20 (40 μL) | 200 μL |
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| SMYD3-EDARADD-20-GORE | 20 (40 μL) | 200 μL |
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| SMYD3-EDARADD-20-GOOR | 20 (40 μL) | 200 μL |
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| SMYD3-EDARADD-20-GOGO | 20 (40 μL) | 200 μL |
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| SMYD3-EDARADD-20-GOGR | 20 (40 μL) | 200 μL |
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| SMYD3-EDARADD-20-GOAQ | 20 (40 μL) | 200 μL |
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| SMYD3-EDARADD-20-GRRE | 20 (40 μL) | 200 μL |
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| SMYD3-EDARADD-20-GROR | 20 (40 μL) | 200 μL |
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| SMYD3-EDARADD-20-GRGO | 20 (40 μL) | 200 μL |
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| SMYD3-EDARADD-20-GRGR | 20 (40 μL) | 200 μL |
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| SMYD3-EDARADD-20-GRAQ | 20 (40 μL) | 200 μL |
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| SMYD3-EDARADD-20-AQRE | 20 (40 μL) | 200 μL |
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| SMYD3-EDARADD-20-AQOR | 20 (40 μL) | 200 μL |
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| SMYD3-EDARADD-20-AQGO | 20 (40 μL) | 200 μL |
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| SMYD3-EDARADD-20-AQGR | 20 (40 μL) | 200 μL |
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| SMYD3-EDARADD-20-AQAQ | 20 (40 μL) | 200 μL |
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SMYD3 Gene Summary
This gene encodes a histone methyltransferase which functions in RNA polymerase II complexes by an interaction with a specific RNA helicase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Name: SET And MYND Domain Containing 3
Chromosome: CHR1: 245912641 -246670644
Locus: 1q44
EDARADD Gene Summary
This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Gene Name: EDAR Associated Death Domain
Chromosome: CHR1: 236557679 -236648008
Locus: 1q42.3-q43
Gene Diseases
The SMYD3 EDARADD Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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