SMYD2-PROX1 Fusion FISH Probe
The SMYD2-PROX1 Fusion FISH Probe is used to confirm a fusion of the SMYD2 and PROX1 genes. The fusion of the SMYD2 and PROX1 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SMYD2-PROX1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SMYD2-PROX1-20-RERE | 20 (40 μL) | 200 μL |
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| SMYD2-PROX1-20-REOR | 20 (40 μL) | 200 μL |
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| SMYD2-PROX1-20-REGO | 20 (40 μL) | 200 μL |
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| SMYD2-PROX1-20-REGR | 20 (40 μL) | 200 μL |
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| SMYD2-PROX1-20-REAQ | 20 (40 μL) | 200 μL |
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| SMYD2-PROX1-20-ORRE | 20 (40 μL) | 200 μL |
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| SMYD2-PROX1-20-OROR | 20 (40 μL) | 200 μL |
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| SMYD2-PROX1-20-ORGO | 20 (40 μL) | 200 μL |
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| SMYD2-PROX1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SMYD2-PROX1-20-GORE | 20 (40 μL) | 200 μL |
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| SMYD2-PROX1-20-GOOR | 20 (40 μL) | 200 μL |
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| SMYD2-PROX1-20-GOGO | 20 (40 μL) | 200 μL |
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| SMYD2-PROX1-20-GOGR | 20 (40 μL) | 200 μL |
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| SMYD2-PROX1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SMYD2-PROX1-20-GRRE | 20 (40 μL) | 200 μL |
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| SMYD2-PROX1-20-GROR | 20 (40 μL) | 200 μL |
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| SMYD2-PROX1-20-GRGO | 20 (40 μL) | 200 μL |
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| SMYD2-PROX1-20-GRGR | 20 (40 μL) | 200 μL |
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| SMYD2-PROX1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SMYD2-PROX1-20-AQRE | 20 (40 μL) | 200 μL |
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| SMYD2-PROX1-20-AQOR | 20 (40 μL) | 200 μL |
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| SMYD2-PROX1-20-AQGO | 20 (40 μL) | 200 μL |
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| SMYD2-PROX1-20-AQGR | 20 (40 μL) | 200 μL |
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| SMYD2-PROX1-20-AQAQ | 20 (40 μL) | 200 μL |
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PROX1 Gene Summary
The protein encoded by this gene is a member of the homeobox transcription factor family. Members of this family contain a homeobox domain that consists of a 60-amino acid helix-turn-helix structure that binds DNA and RNA. The protein encoded by this gene is conserved across vertebrates and may play an essential role during development. Altered levels of this protein have been reported in cancers of different organs, such as colon, brain, blood, breast, pancreas, liver and esophagus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
Gene Name: Prospero Homeobox 1
Chromosome: CHR1: 214161859 -214209762
Locus: 1q32.3
SMYD2 Gene Summary
SET domain-containing proteins, such as SMYD2, catalyze lysine methylation (Brown et al., 2006 [PubMed 16805913]).[supplied by OMIM, Nov 2008]
Gene Name: SET And MYND Domain Containing 2
Chromosome: CHR1: 214454564 -214510477
Locus: 1q32.3
Gene Diseases
The SMYD2 PROX1 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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