SMURF1-PTCD1 Fusion FISH Probe
The SMURF1-PTCD1 Fusion FISH Probe is used to confirm a fusion of the SMURF1 and PTCD1 genes. The fusion of the SMURF1 and PTCD1 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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SMURF1-PTCD1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL | ||
SMURF1-PTCD1-20-RERE | 20 (40 μL) | 200 μL | ||
SMURF1-PTCD1-20-REOR | 20 (40 μL) | 200 μL | ||
SMURF1-PTCD1-20-REGO | 20 (40 μL) | 200 μL | ||
SMURF1-PTCD1-20-REGR | 20 (40 μL) | 200 μL | ||
SMURF1-PTCD1-20-REAQ | 20 (40 μL) | 200 μL | ||
SMURF1-PTCD1-20-ORRE | 20 (40 μL) | 200 μL | ||
SMURF1-PTCD1-20-OROR | 20 (40 μL) | 200 μL | ||
SMURF1-PTCD1-20-ORGO | 20 (40 μL) | 200 μL | ||
SMURF1-PTCD1-20-ORAQ | 20 (40 μL) | 200 μL | ||
SMURF1-PTCD1-20-GORE | 20 (40 μL) | 200 μL | ||
SMURF1-PTCD1-20-GOOR | 20 (40 μL) | 200 μL | ||
SMURF1-PTCD1-20-GOGO | 20 (40 μL) | 200 μL | ||
SMURF1-PTCD1-20-GOGR | 20 (40 μL) | 200 μL | ||
SMURF1-PTCD1-20-GOAQ | 20 (40 μL) | 200 μL | ||
SMURF1-PTCD1-20-GRRE | 20 (40 μL) | 200 μL | ||
SMURF1-PTCD1-20-GROR | 20 (40 μL) | 200 μL | ||
SMURF1-PTCD1-20-GRGO | 20 (40 μL) | 200 μL | ||
SMURF1-PTCD1-20-GRGR | 20 (40 μL) | 200 μL | ||
SMURF1-PTCD1-20-GRAQ | 20 (40 μL) | 200 μL | ||
SMURF1-PTCD1-20-AQRE | 20 (40 μL) | 200 μL | ||
SMURF1-PTCD1-20-AQOR | 20 (40 μL) | 200 μL | ||
SMURF1-PTCD1-20-AQGO | 20 (40 μL) | 200 μL | ||
SMURF1-PTCD1-20-AQGR | 20 (40 μL) | 200 μL | ||
SMURF1-PTCD1-20-AQAQ | 20 (40 μL) | 200 μL |
PTCD1 Gene Summary
This gene encodes a mitochondrial protein that binds leucine tRNAs and other mitochondrial RNAs and plays a role in the regulation of translation. Increased expression of this gene results in decreased mitochondrial leucine tRNA levels. Naturally occurring read-through transcription exists between upstream ATP5J2 (ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2) and this gene. [provided by RefSeq, Aug 2015]
Gene Name: Pentatricopeptide Repeat Domain 1
Chromosome: CHR7: 99014361 -99036462
Locus: 7q22.1
SMURF1 Gene Summary
This gene encodes a ubiquitin ligase that is specific for receptor-regulated SMAD proteins in the bone morphogenetic protein (BMP) pathway. This protein plays a key roll in the regulation of cell motility, cell signalling, and cell polarity. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Dec 2010]
Gene Name: SMAD Specific E3 Ubiquitin Protein Ligase 1
Chromosome: CHR7: 98625057 -98741743
Locus: 7q22.1
Gene Diseases
The SMURF1 PTCD1 Fusion has been associated with the following diseases:
Disease Name |
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Esophageal Carcinoma |
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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