SMURF1-AKAP9 Fusion FISH Probe
The SMURF1-AKAP9 Fusion FISH Probe is used to confirm a fusion of the SMURF1 and AKAP9 genes. The fusion of the SMURF1 and AKAP9 genes has been associated with Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SMURF1-AKAP9-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SMURF1-AKAP9-20-RERE | 20 (40 μL) | 200 μL |
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| SMURF1-AKAP9-20-REOR | 20 (40 μL) | 200 μL |
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| SMURF1-AKAP9-20-REGO | 20 (40 μL) | 200 μL |
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| SMURF1-AKAP9-20-REGR | 20 (40 μL) | 200 μL |
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| SMURF1-AKAP9-20-REAQ | 20 (40 μL) | 200 μL |
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| SMURF1-AKAP9-20-ORRE | 20 (40 μL) | 200 μL |
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| SMURF1-AKAP9-20-OROR | 20 (40 μL) | 200 μL |
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| SMURF1-AKAP9-20-ORGO | 20 (40 μL) | 200 μL |
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| SMURF1-AKAP9-20-ORAQ | 20 (40 μL) | 200 μL |
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| SMURF1-AKAP9-20-GORE | 20 (40 μL) | 200 μL |
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| SMURF1-AKAP9-20-GOOR | 20 (40 μL) | 200 μL |
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| SMURF1-AKAP9-20-GOGO | 20 (40 μL) | 200 μL |
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| SMURF1-AKAP9-20-GOGR | 20 (40 μL) | 200 μL |
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| SMURF1-AKAP9-20-GOAQ | 20 (40 μL) | 200 μL |
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| SMURF1-AKAP9-20-GRRE | 20 (40 μL) | 200 μL |
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| SMURF1-AKAP9-20-GROR | 20 (40 μL) | 200 μL |
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| SMURF1-AKAP9-20-GRGO | 20 (40 μL) | 200 μL |
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| SMURF1-AKAP9-20-GRGR | 20 (40 μL) | 200 μL |
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| SMURF1-AKAP9-20-GRAQ | 20 (40 μL) | 200 μL |
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| SMURF1-AKAP9-20-AQRE | 20 (40 μL) | 200 μL |
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| SMURF1-AKAP9-20-AQOR | 20 (40 μL) | 200 μL |
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| SMURF1-AKAP9-20-AQGO | 20 (40 μL) | 200 μL |
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| SMURF1-AKAP9-20-AQGR | 20 (40 μL) | 200 μL |
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| SMURF1-AKAP9-20-AQAQ | 20 (40 μL) | 200 μL |
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AKAP9 Gene Summary
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternate splicing of this gene results in at least two isoforms that localize to the centrosome and the Golgi apparatus, and interact with numerous signaling proteins from multiple signal transduction pathways. These signaling proteins include type II protein kinase A, serine/threonine kinase protein kinase N, protein phosphatase 1, protein phosphatase 2a, protein kinase C-epsilon and phosphodiesterase 4D3. [provided by RefSeq, Aug 2008]
Gene Name: A-kinase Anchoring Protein 9
Chromosome: CHR7: 91570188 -91739987
Locus: 7q21.2
SMURF1 Gene Summary
This gene encodes a ubiquitin ligase that is specific for receptor-regulated SMAD proteins in the bone morphogenetic protein (BMP) pathway. This protein plays a key roll in the regulation of cell motility, cell signalling, and cell polarity. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Dec 2010]
Gene Name: SMAD Specific E3 Ubiquitin Protein Ligase 1
Chromosome: CHR7: 98625057 -98741743
Locus: 7q22.1
Gene Diseases
The SMURF1 AKAP9 Fusion has been associated with the following diseases:
| Disease Name |
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| Pancreatic Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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