SMG7-GLT25D2 Fusion FISH Probe
The SMG7-GLT25D2 Fusion FISH Probe is used to confirm a fusion of the SMG7 and GLT25D2 genes. The fusion of the SMG7 and GLT25D2 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SMG7-GLT25D2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| SMG7-GLT25D2-20-RERE | 20 (40 μL) | 200 μL |
|
|
| SMG7-GLT25D2-20-REOR | 20 (40 μL) | 200 μL |
|
|
| SMG7-GLT25D2-20-REGO | 20 (40 μL) | 200 μL |
|
|
| SMG7-GLT25D2-20-REGR | 20 (40 μL) | 200 μL |
|
|
| SMG7-GLT25D2-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| SMG7-GLT25D2-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| SMG7-GLT25D2-20-OROR | 20 (40 μL) | 200 μL |
|
|
| SMG7-GLT25D2-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| SMG7-GLT25D2-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| SMG7-GLT25D2-20-GORE | 20 (40 μL) | 200 μL |
|
|
| SMG7-GLT25D2-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| SMG7-GLT25D2-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| SMG7-GLT25D2-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| SMG7-GLT25D2-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| SMG7-GLT25D2-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| SMG7-GLT25D2-20-GROR | 20 (40 μL) | 200 μL |
|
|
| SMG7-GLT25D2-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| SMG7-GLT25D2-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| SMG7-GLT25D2-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| SMG7-GLT25D2-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| SMG7-GLT25D2-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| SMG7-GLT25D2-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| SMG7-GLT25D2-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| SMG7-GLT25D2-20-AQAQ | 20 (40 μL) | 200 μL |
|
SMG7 Gene Summary
This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD); a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2011]
Gene Name: SMG7, Nonsense Mediated MRNA Decay Factor
Chromosome: CHR1: 183441505 -183523328
Locus: 1q25.3
Gene Diseases
The SMG7 GLT25D2 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|