SMEK2-KYNU Fusion FISH Probe
The SMEK2-KYNU Fusion FISH Probe is used to confirm a fusion of the SMEK2 and KYNU genes. The fusion of the SMEK2 and KYNU genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SMEK2-KYNU-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SMEK2-KYNU-20-RERE | 20 (40 μL) | 200 μL |
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| SMEK2-KYNU-20-REOR | 20 (40 μL) | 200 μL |
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| SMEK2-KYNU-20-REGO | 20 (40 μL) | 200 μL |
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| SMEK2-KYNU-20-REGR | 20 (40 μL) | 200 μL |
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| SMEK2-KYNU-20-REAQ | 20 (40 μL) | 200 μL |
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| SMEK2-KYNU-20-ORRE | 20 (40 μL) | 200 μL |
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| SMEK2-KYNU-20-OROR | 20 (40 μL) | 200 μL |
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| SMEK2-KYNU-20-ORGO | 20 (40 μL) | 200 μL |
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| SMEK2-KYNU-20-ORAQ | 20 (40 μL) | 200 μL |
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| SMEK2-KYNU-20-GORE | 20 (40 μL) | 200 μL |
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| SMEK2-KYNU-20-GOOR | 20 (40 μL) | 200 μL |
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| SMEK2-KYNU-20-GOGO | 20 (40 μL) | 200 μL |
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| SMEK2-KYNU-20-GOGR | 20 (40 μL) | 200 μL |
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| SMEK2-KYNU-20-GOAQ | 20 (40 μL) | 200 μL |
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| SMEK2-KYNU-20-GRRE | 20 (40 μL) | 200 μL |
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| SMEK2-KYNU-20-GROR | 20 (40 μL) | 200 μL |
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| SMEK2-KYNU-20-GRGO | 20 (40 μL) | 200 μL |
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| SMEK2-KYNU-20-GRGR | 20 (40 μL) | 200 μL |
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| SMEK2-KYNU-20-GRAQ | 20 (40 μL) | 200 μL |
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| SMEK2-KYNU-20-AQRE | 20 (40 μL) | 200 μL |
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| SMEK2-KYNU-20-AQOR | 20 (40 μL) | 200 μL |
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| SMEK2-KYNU-20-AQGO | 20 (40 μL) | 200 μL |
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| SMEK2-KYNU-20-AQGR | 20 (40 μL) | 200 μL |
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| SMEK2-KYNU-20-AQAQ | 20 (40 μL) | 200 μL |
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KYNU Gene Summary
Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]
Gene Name: Kynureninase
Chromosome: CHR2: 143635194 -143799885
Locus: 2q22.2
Gene Diseases
The SMEK2 KYNU Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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