SMEK2-IL18RAP Fusion FISH Probe
The SMEK2-IL18RAP Fusion FISH Probe is used to confirm a fusion of the SMEK2 and IL18RAP genes. The fusion of the SMEK2 and IL18RAP genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SMEK2-IL18RAP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SMEK2-IL18RAP-20-RERE | 20 (40 μL) | 200 μL |
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| SMEK2-IL18RAP-20-REOR | 20 (40 μL) | 200 μL |
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| SMEK2-IL18RAP-20-REGO | 20 (40 μL) | 200 μL |
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| SMEK2-IL18RAP-20-REGR | 20 (40 μL) | 200 μL |
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| SMEK2-IL18RAP-20-REAQ | 20 (40 μL) | 200 μL |
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| SMEK2-IL18RAP-20-ORRE | 20 (40 μL) | 200 μL |
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| SMEK2-IL18RAP-20-OROR | 20 (40 μL) | 200 μL |
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| SMEK2-IL18RAP-20-ORGO | 20 (40 μL) | 200 μL |
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| SMEK2-IL18RAP-20-ORAQ | 20 (40 μL) | 200 μL |
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| SMEK2-IL18RAP-20-GORE | 20 (40 μL) | 200 μL |
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| SMEK2-IL18RAP-20-GOOR | 20 (40 μL) | 200 μL |
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| SMEK2-IL18RAP-20-GOGO | 20 (40 μL) | 200 μL |
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| SMEK2-IL18RAP-20-GOGR | 20 (40 μL) | 200 μL |
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| SMEK2-IL18RAP-20-GOAQ | 20 (40 μL) | 200 μL |
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| SMEK2-IL18RAP-20-GRRE | 20 (40 μL) | 200 μL |
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| SMEK2-IL18RAP-20-GROR | 20 (40 μL) | 200 μL |
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| SMEK2-IL18RAP-20-GRGO | 20 (40 μL) | 200 μL |
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| SMEK2-IL18RAP-20-GRGR | 20 (40 μL) | 200 μL |
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| SMEK2-IL18RAP-20-GRAQ | 20 (40 μL) | 200 μL |
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| SMEK2-IL18RAP-20-AQRE | 20 (40 μL) | 200 μL |
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| SMEK2-IL18RAP-20-AQOR | 20 (40 μL) | 200 μL |
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| SMEK2-IL18RAP-20-AQGO | 20 (40 μL) | 200 μL |
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| SMEK2-IL18RAP-20-AQGR | 20 (40 μL) | 200 μL |
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| SMEK2-IL18RAP-20-AQAQ | 20 (40 μL) | 200 μL |
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IL18RAP Gene Summary
The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for interleukin 18 (IL18), a proinflammatory cytokine involved in inducing cell-mediated immunity. This protein enhances the IL18-binding activity of the IL18 receptor and plays a role in signaling by IL18. Mutations in this gene are associated with Crohn's disease and inflammatory bowel disease, and susceptibility to celiac disease and leprosy. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]
Gene Name: Interleukin 18 Receptor Accessory Protein
Chromosome: CHR2: 103035253 -103069024
Locus: 2q12.1
Gene Diseases
The SMEK2 IL18RAP Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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