SMARCA2-BEND2 Fusion FISH Probe
The SMARCA2-BEND2 Fusion FISH Probe is used to confirm a fusion of the SMARCA2 and BEND2 genes. The fusion of the SMARCA2 and BEND2 genes has been associated with Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SMARCA2-BEND2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SMARCA2-BEND2-20-RERE | 20 (40 μL) | 200 μL |
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| SMARCA2-BEND2-20-REOR | 20 (40 μL) | 200 μL |
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| SMARCA2-BEND2-20-REGO | 20 (40 μL) | 200 μL |
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| SMARCA2-BEND2-20-REGR | 20 (40 μL) | 200 μL |
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| SMARCA2-BEND2-20-REAQ | 20 (40 μL) | 200 μL |
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| SMARCA2-BEND2-20-ORRE | 20 (40 μL) | 200 μL |
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| SMARCA2-BEND2-20-OROR | 20 (40 μL) | 200 μL |
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| SMARCA2-BEND2-20-ORGO | 20 (40 μL) | 200 μL |
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| SMARCA2-BEND2-20-ORAQ | 20 (40 μL) | 200 μL |
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| SMARCA2-BEND2-20-GORE | 20 (40 μL) | 200 μL |
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| SMARCA2-BEND2-20-GOOR | 20 (40 μL) | 200 μL |
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| SMARCA2-BEND2-20-GOGO | 20 (40 μL) | 200 μL |
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| SMARCA2-BEND2-20-GOGR | 20 (40 μL) | 200 μL |
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| SMARCA2-BEND2-20-GOAQ | 20 (40 μL) | 200 μL |
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| SMARCA2-BEND2-20-GRRE | 20 (40 μL) | 200 μL |
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| SMARCA2-BEND2-20-GROR | 20 (40 μL) | 200 μL |
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| SMARCA2-BEND2-20-GRGO | 20 (40 μL) | 200 μL |
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| SMARCA2-BEND2-20-GRGR | 20 (40 μL) | 200 μL |
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| SMARCA2-BEND2-20-GRAQ | 20 (40 μL) | 200 μL |
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| SMARCA2-BEND2-20-AQRE | 20 (40 μL) | 200 μL |
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| SMARCA2-BEND2-20-AQOR | 20 (40 μL) | 200 μL |
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| SMARCA2-BEND2-20-AQGO | 20 (40 μL) | 200 μL |
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| SMARCA2-BEND2-20-AQGR | 20 (40 μL) | 200 μL |
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| SMARCA2-BEND2-20-AQAQ | 20 (40 μL) | 200 μL |
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SMARCA2 Gene Summary
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism. [provided by RefSeq, Jan 2014]
Gene Name: SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A, Member 2
Chromosome: CHR9: 2015341 -2193623
Locus: 9p24.3
BEND2 Gene Summary
This gene encodes a protein which has two BEN domains in the C-terminus. These domains are found in proteins which participate in protein and DNA interactions which occur during chromatin restructuring or transcription. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Gene Name: BEN Domain Containing 2
Chromosome: CHRX: 18181050 -18239024
Locus: Xp22.13
Gene Diseases
The SMARCA2 BEND2 Fusion has been associated with the following diseases:
| Disease Name |
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| Pancreatic Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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