SMAD5-COL5A1 Fusion FISH Probe
The SMAD5-COL5A1 Fusion FISH Probe is used to confirm a fusion of the SMAD5 and COL5A1 genes. The fusion of the SMAD5 and COL5A1 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SMAD5-COL5A1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| SMAD5-COL5A1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| SMAD5-COL5A1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| SMAD5-COL5A1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| SMAD5-COL5A1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| SMAD5-COL5A1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| SMAD5-COL5A1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| SMAD5-COL5A1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| SMAD5-COL5A1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| SMAD5-COL5A1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| SMAD5-COL5A1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| SMAD5-COL5A1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| SMAD5-COL5A1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| SMAD5-COL5A1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| SMAD5-COL5A1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| SMAD5-COL5A1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| SMAD5-COL5A1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| SMAD5-COL5A1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| SMAD5-COL5A1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| SMAD5-COL5A1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| SMAD5-COL5A1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| SMAD5-COL5A1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| SMAD5-COL5A1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| SMAD5-COL5A1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| SMAD5-COL5A1-20-AQAQ | 20 (40 μL) | 200 μL |
|
COL5A1 Gene Summary
This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. The encoded procollagen protein occurs commonly as the heterotrimer pro-alpha1(V)-pro-alpha1(V)-pro-alpha2(V). Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]
Gene Name: Collagen Type V Alpha 1 Chain
Chromosome: CHR9: 137533651 -137736688
Locus: 9q34.3
SMAD5 Gene Summary
The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Gene Name: SMAD Family Member 5
Chromosome: CHR5: 135468535 -135518422
Locus: 5q31.1
Gene Diseases
The SMAD5 COL5A1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|