SLMAP-CUL4B Fusion FISH Probe
The SLMAP-CUL4B Fusion FISH Probe is used to confirm a fusion of the SLMAP and CUL4B genes. The fusion of the SLMAP and CUL4B genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SLMAP-CUL4B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SLMAP-CUL4B-20-RERE | 20 (40 μL) | 200 μL |
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| SLMAP-CUL4B-20-REOR | 20 (40 μL) | 200 μL |
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| SLMAP-CUL4B-20-REGO | 20 (40 μL) | 200 μL |
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| SLMAP-CUL4B-20-REGR | 20 (40 μL) | 200 μL |
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| SLMAP-CUL4B-20-REAQ | 20 (40 μL) | 200 μL |
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| SLMAP-CUL4B-20-ORRE | 20 (40 μL) | 200 μL |
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| SLMAP-CUL4B-20-OROR | 20 (40 μL) | 200 μL |
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| SLMAP-CUL4B-20-ORGO | 20 (40 μL) | 200 μL |
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| SLMAP-CUL4B-20-ORAQ | 20 (40 μL) | 200 μL |
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| SLMAP-CUL4B-20-GORE | 20 (40 μL) | 200 μL |
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| SLMAP-CUL4B-20-GOOR | 20 (40 μL) | 200 μL |
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| SLMAP-CUL4B-20-GOGO | 20 (40 μL) | 200 μL |
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| SLMAP-CUL4B-20-GOGR | 20 (40 μL) | 200 μL |
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| SLMAP-CUL4B-20-GOAQ | 20 (40 μL) | 200 μL |
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| SLMAP-CUL4B-20-GRRE | 20 (40 μL) | 200 μL |
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| SLMAP-CUL4B-20-GROR | 20 (40 μL) | 200 μL |
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| SLMAP-CUL4B-20-GRGO | 20 (40 μL) | 200 μL |
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| SLMAP-CUL4B-20-GRGR | 20 (40 μL) | 200 μL |
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| SLMAP-CUL4B-20-GRAQ | 20 (40 μL) | 200 μL |
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| SLMAP-CUL4B-20-AQRE | 20 (40 μL) | 200 μL |
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| SLMAP-CUL4B-20-AQOR | 20 (40 μL) | 200 μL |
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| SLMAP-CUL4B-20-AQGO | 20 (40 μL) | 200 μL |
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| SLMAP-CUL4B-20-AQGR | 20 (40 μL) | 200 μL |
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| SLMAP-CUL4B-20-AQAQ | 20 (40 μL) | 200 μL |
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SLMAP Gene Summary
This gene encodes a component of a conserved striatin-interacting phosphatase and kinase complex. Striatin family complexes participate in a variety of cellular processes including signaling, cell cycle control, cell migration, Golgi assembly, and apoptosis. The protein encoded by this gene is a coiled-coil, tail-anchored membrane protein with a single C-terminal transmembrane domain that is posttranslationally inserted into membranes. Mutations in this gene are associated with Brugada syndrome, a cardiac channelopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
Gene Name: Sarcolemma Associated Protein
Chromosome: CHR3: 57743173 -57914894
Locus: 3p14.3
CUL4B Gene Summary
This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Cullin 4B
Chromosome: CHRX: 119658445 -119709684
Locus: Xq24
Gene Diseases
The SLMAP CUL4B Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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