SLC9A8-PTGIS Fusion FISH Probe
The SLC9A8-PTGIS Fusion FISH Probe is used to confirm a fusion of the SLC9A8 and PTGIS genes. The fusion of the SLC9A8 and PTGIS genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SLC9A8-PTGIS-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SLC9A8-PTGIS-20-RERE | 20 (40 μL) | 200 μL |
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| SLC9A8-PTGIS-20-REOR | 20 (40 μL) | 200 μL |
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| SLC9A8-PTGIS-20-REGO | 20 (40 μL) | 200 μL |
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| SLC9A8-PTGIS-20-REGR | 20 (40 μL) | 200 μL |
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| SLC9A8-PTGIS-20-REAQ | 20 (40 μL) | 200 μL |
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| SLC9A8-PTGIS-20-ORRE | 20 (40 μL) | 200 μL |
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| SLC9A8-PTGIS-20-OROR | 20 (40 μL) | 200 μL |
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| SLC9A8-PTGIS-20-ORGO | 20 (40 μL) | 200 μL |
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| SLC9A8-PTGIS-20-ORAQ | 20 (40 μL) | 200 μL |
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| SLC9A8-PTGIS-20-GORE | 20 (40 μL) | 200 μL |
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| SLC9A8-PTGIS-20-GOOR | 20 (40 μL) | 200 μL |
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| SLC9A8-PTGIS-20-GOGO | 20 (40 μL) | 200 μL |
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| SLC9A8-PTGIS-20-GOGR | 20 (40 μL) | 200 μL |
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| SLC9A8-PTGIS-20-GOAQ | 20 (40 μL) | 200 μL |
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| SLC9A8-PTGIS-20-GRRE | 20 (40 μL) | 200 μL |
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| SLC9A8-PTGIS-20-GROR | 20 (40 μL) | 200 μL |
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| SLC9A8-PTGIS-20-GRGO | 20 (40 μL) | 200 μL |
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| SLC9A8-PTGIS-20-GRGR | 20 (40 μL) | 200 μL |
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| SLC9A8-PTGIS-20-GRAQ | 20 (40 μL) | 200 μL |
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| SLC9A8-PTGIS-20-AQRE | 20 (40 μL) | 200 μL |
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| SLC9A8-PTGIS-20-AQOR | 20 (40 μL) | 200 μL |
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| SLC9A8-PTGIS-20-AQGO | 20 (40 μL) | 200 μL |
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| SLC9A8-PTGIS-20-AQGR | 20 (40 μL) | 200 μL |
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| SLC9A8-PTGIS-20-AQAQ | 20 (40 μL) | 200 μL |
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PTGIS Gene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. [provided by RefSeq, Jul 2008]
Gene Name: Prostaglandin I2 Synthase
Chromosome: CHR20: 48120410 -48184707
Locus: 20q13.13
SLC9A8 Gene Summary
Sodium-hydrogen exchangers (NHEs), such as SLC9A8, are integral transmembrane proteins that exchange extracellular Na+ for intracellular H+. NHEs have multiple functions, including intracellular pH homeostasis, cell volume regulation, and electroneutral NaCl absorption in epithelia (Xu et al., 2008 [PubMed 18209477]).[supplied by OMIM, Apr 2009]
Gene Name: Solute Carrier Family 9 Member A8
Chromosome: CHR20: 48429249 -48508772
Locus: 20q13.13
Gene Diseases
The SLC9A8 PTGIS Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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