SLC7A7-ACIN1 Fusion FISH Probe
The SLC7A7-ACIN1 Fusion FISH Probe is used to confirm a fusion of the SLC7A7 and ACIN1 genes. The fusion of the SLC7A7 and ACIN1 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SLC7A7-ACIN1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SLC7A7-ACIN1-20-RERE | 20 (40 μL) | 200 μL |
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| SLC7A7-ACIN1-20-REOR | 20 (40 μL) | 200 μL |
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| SLC7A7-ACIN1-20-REGO | 20 (40 μL) | 200 μL |
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| SLC7A7-ACIN1-20-REGR | 20 (40 μL) | 200 μL |
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| SLC7A7-ACIN1-20-REAQ | 20 (40 μL) | 200 μL |
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| SLC7A7-ACIN1-20-ORRE | 20 (40 μL) | 200 μL |
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| SLC7A7-ACIN1-20-OROR | 20 (40 μL) | 200 μL |
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| SLC7A7-ACIN1-20-ORGO | 20 (40 μL) | 200 μL |
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| SLC7A7-ACIN1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SLC7A7-ACIN1-20-GORE | 20 (40 μL) | 200 μL |
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| SLC7A7-ACIN1-20-GOOR | 20 (40 μL) | 200 μL |
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| SLC7A7-ACIN1-20-GOGO | 20 (40 μL) | 200 μL |
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| SLC7A7-ACIN1-20-GOGR | 20 (40 μL) | 200 μL |
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| SLC7A7-ACIN1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SLC7A7-ACIN1-20-GRRE | 20 (40 μL) | 200 μL |
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| SLC7A7-ACIN1-20-GROR | 20 (40 μL) | 200 μL |
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| SLC7A7-ACIN1-20-GRGO | 20 (40 μL) | 200 μL |
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| SLC7A7-ACIN1-20-GRGR | 20 (40 μL) | 200 μL |
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| SLC7A7-ACIN1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SLC7A7-ACIN1-20-AQRE | 20 (40 μL) | 200 μL |
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| SLC7A7-ACIN1-20-AQOR | 20 (40 μL) | 200 μL |
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| SLC7A7-ACIN1-20-AQGO | 20 (40 μL) | 200 μL |
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| SLC7A7-ACIN1-20-AQGR | 20 (40 μL) | 200 μL |
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| SLC7A7-ACIN1-20-AQAQ | 20 (40 μL) | 200 μL |
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SLC7A7 Gene Summary
The protein encoded by this gene is the light subunit of a cationic amino acid transporter. This sodium-independent transporter is formed when the light subunit encoded by this gene dimerizes with the heavy subunit transporter protein SLC3A2. This transporter is found in epithelial cell membranes where it transfers cationic and large neutral amino acids from the cell to the extracellular space. Defects in this gene are a cause of lysinuric protein intolerance (LPI). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2011]
Gene Name: Solute Carrier Family 7 Member 7
Chromosome: CHR14: 23242431 -23289020
Locus: 14q11.2
ACIN1 Gene Summary
Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3, without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
Gene Name: Apoptotic Chromatin Condensation Inducer 1
Chromosome: CHR14: 23527773 -23564823
Locus: 14q11.2
Gene Diseases
The SLC7A7 ACIN1 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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