SLC47A2-ALDH3A1 Fusion FISH Probe
The SLC47A2-ALDH3A1 Fusion FISH Probe is used to confirm a fusion of the SLC47A2 and ALDH3A1 genes. The fusion of the SLC47A2 and ALDH3A1 genes has been associated with Kidney Renal Papillary Cell Carcinoma, and Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SLC47A2-ALDH3A1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SLC47A2-ALDH3A1-20-RERE | 20 (40 μL) | 200 μL |
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| SLC47A2-ALDH3A1-20-REOR | 20 (40 μL) | 200 μL |
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| SLC47A2-ALDH3A1-20-REGO | 20 (40 μL) | 200 μL |
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| SLC47A2-ALDH3A1-20-REGR | 20 (40 μL) | 200 μL |
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| SLC47A2-ALDH3A1-20-REAQ | 20 (40 μL) | 200 μL |
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| SLC47A2-ALDH3A1-20-ORRE | 20 (40 μL) | 200 μL |
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| SLC47A2-ALDH3A1-20-OROR | 20 (40 μL) | 200 μL |
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| SLC47A2-ALDH3A1-20-ORGO | 20 (40 μL) | 200 μL |
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| SLC47A2-ALDH3A1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SLC47A2-ALDH3A1-20-GORE | 20 (40 μL) | 200 μL |
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| SLC47A2-ALDH3A1-20-GOOR | 20 (40 μL) | 200 μL |
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| SLC47A2-ALDH3A1-20-GOGO | 20 (40 μL) | 200 μL |
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| SLC47A2-ALDH3A1-20-GOGR | 20 (40 μL) | 200 μL |
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| SLC47A2-ALDH3A1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SLC47A2-ALDH3A1-20-GRRE | 20 (40 μL) | 200 μL |
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| SLC47A2-ALDH3A1-20-GROR | 20 (40 μL) | 200 μL |
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| SLC47A2-ALDH3A1-20-GRGO | 20 (40 μL) | 200 μL |
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| SLC47A2-ALDH3A1-20-GRGR | 20 (40 μL) | 200 μL |
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| SLC47A2-ALDH3A1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SLC47A2-ALDH3A1-20-AQRE | 20 (40 μL) | 200 μL |
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| SLC47A2-ALDH3A1-20-AQOR | 20 (40 μL) | 200 μL |
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| SLC47A2-ALDH3A1-20-AQGO | 20 (40 μL) | 200 μL |
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| SLC47A2-ALDH3A1-20-AQGR | 20 (40 μL) | 200 μL |
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| SLC47A2-ALDH3A1-20-AQAQ | 20 (40 μL) | 200 μL |
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ALDH3A1 Gene Summary
Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]
Gene Name: Aldehyde Dehydrogenase 3 Family Member A1
Chromosome: CHR17: 19641297 -19651746
Locus: 17p11.2
SLC47A2 Gene Summary
This gene encodes a protein belonging to a family of transporters involved in excretion of toxic electrolytes, both endogenous and exogenous, through urine and bile. This transporter family shares homology with the bacterial MATE (multidrug and toxin extrusion) protein family responsible for drug resistance. This gene is one of two members of the MATE transporter family located near each other on chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Solute Carrier Family 47 Member 2
Chromosome: CHR17: 19581627 -19620043
Locus: 17p11.2
Gene Diseases
The SLC47A2 ALDH3A1 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Papillary Cell Carcinoma |
| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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