SLC39A14-PRKDC Fusion FISH Probe
The SLC39A14-PRKDC Fusion FISH Probe is used to confirm a fusion of the SLC39A14 and PRKDC genes. The fusion of the SLC39A14 and PRKDC genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SLC39A14-PRKDC-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-PRKDC-20-RERE | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-PRKDC-20-REOR | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-PRKDC-20-REGO | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-PRKDC-20-REGR | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-PRKDC-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-PRKDC-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-PRKDC-20-OROR | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-PRKDC-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-PRKDC-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-PRKDC-20-GORE | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-PRKDC-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-PRKDC-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-PRKDC-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-PRKDC-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-PRKDC-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-PRKDC-20-GROR | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-PRKDC-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-PRKDC-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-PRKDC-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-PRKDC-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-PRKDC-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-PRKDC-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-PRKDC-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-PRKDC-20-AQAQ | 20 (40 μL) | 200 μL |
|
PRKDC Gene Summary
This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.[provided by RefSeq, Jul 2010]
Gene Name: Protein Kinase, DNA-activated, Catalytic Polypeptide
Chromosome: CHR8: 48685668 -48872743
Locus: 8q11.21
SLC39A14 Gene Summary
This gene encodes a member of the the SLC39A family of divalent metal transporters that mediates the cellular uptake of manganese, zinc, iron, and cadmium. The encoded protein contains eight transmembrane domains, a histidine-rich motif, and a metalloprotease motif, and is expressed on the plasma membrane and the endocytic vesicle membrane. It is an important transporter of nontransferrin-bound iron and a critical regulator of manganese homeostasis. Naturally occurring mutations in this gene are associated with neurodegeneration with brain iron accumulation and early-onset parkinsonism-dystonia with hypermanganesemia. [provided by RefSeq, May 2017]
Gene Name: Solute Carrier Family 39 Member 14
Chromosome: CHR8: 22224761 -22291640
Locus: 8p21.3
Gene Diseases
The SLC39A14 PRKDC Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|