SLC39A14-PIWIL2 Fusion FISH Probe
The SLC39A14-PIWIL2 Fusion FISH Probe is used to confirm a fusion of the SLC39A14 and PIWIL2 genes. The fusion of the SLC39A14 and PIWIL2 genes has been associated with Stomach Adenocarcinoma, and Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SLC39A14-PIWIL2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SLC39A14-PIWIL2-20-RERE | 20 (40 μL) | 200 μL |
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| SLC39A14-PIWIL2-20-REOR | 20 (40 μL) | 200 μL |
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| SLC39A14-PIWIL2-20-REGO | 20 (40 μL) | 200 μL |
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| SLC39A14-PIWIL2-20-REGR | 20 (40 μL) | 200 μL |
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| SLC39A14-PIWIL2-20-REAQ | 20 (40 μL) | 200 μL |
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| SLC39A14-PIWIL2-20-ORRE | 20 (40 μL) | 200 μL |
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| SLC39A14-PIWIL2-20-OROR | 20 (40 μL) | 200 μL |
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| SLC39A14-PIWIL2-20-ORGO | 20 (40 μL) | 200 μL |
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| SLC39A14-PIWIL2-20-ORAQ | 20 (40 μL) | 200 μL |
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| SLC39A14-PIWIL2-20-GORE | 20 (40 μL) | 200 μL |
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| SLC39A14-PIWIL2-20-GOOR | 20 (40 μL) | 200 μL |
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| SLC39A14-PIWIL2-20-GOGO | 20 (40 μL) | 200 μL |
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| SLC39A14-PIWIL2-20-GOGR | 20 (40 μL) | 200 μL |
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| SLC39A14-PIWIL2-20-GOAQ | 20 (40 μL) | 200 μL |
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| SLC39A14-PIWIL2-20-GRRE | 20 (40 μL) | 200 μL |
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| SLC39A14-PIWIL2-20-GROR | 20 (40 μL) | 200 μL |
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| SLC39A14-PIWIL2-20-GRGO | 20 (40 μL) | 200 μL |
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| SLC39A14-PIWIL2-20-GRGR | 20 (40 μL) | 200 μL |
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| SLC39A14-PIWIL2-20-GRAQ | 20 (40 μL) | 200 μL |
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| SLC39A14-PIWIL2-20-AQRE | 20 (40 μL) | 200 μL |
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| SLC39A14-PIWIL2-20-AQOR | 20 (40 μL) | 200 μL |
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| SLC39A14-PIWIL2-20-AQGO | 20 (40 μL) | 200 μL |
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| SLC39A14-PIWIL2-20-AQGR | 20 (40 μL) | 200 μL |
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| SLC39A14-PIWIL2-20-AQAQ | 20 (40 μL) | 200 μL |
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SLC39A14 Gene Summary
This gene encodes a member of the the SLC39A family of divalent metal transporters that mediates the cellular uptake of manganese, zinc, iron, and cadmium. The encoded protein contains eight transmembrane domains, a histidine-rich motif, and a metalloprotease motif, and is expressed on the plasma membrane and the endocytic vesicle membrane. It is an important transporter of nontransferrin-bound iron and a critical regulator of manganese homeostasis. Naturally occurring mutations in this gene are associated with neurodegeneration with brain iron accumulation and early-onset parkinsonism-dystonia with hypermanganesemia. [provided by RefSeq, May 2017]
Gene Name: Solute Carrier Family 39 Member 14
Chromosome: CHR8: 22224761 -22291640
Locus: 8p21.3
PIWIL2 Gene Summary
PIWIL2 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells (Sasaki et al., 2003 [PubMed 12906857]).[supplied by OMIM, Mar 2008]
Gene Name: Piwi Like RNA-mediated Gene Silencing 2
Chromosome: CHR8: 22132809 -22213584
Locus: 8p21.3
Gene Diseases
The SLC39A14 PIWIL2 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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