SLC37A1-MTA1 Fusion FISH Probe
The SLC37A1-MTA1 Fusion FISH Probe is used to confirm a fusion of the SLC37A1 and MTA1 genes. The fusion of the SLC37A1 and MTA1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SLC37A1-MTA1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SLC37A1-MTA1-20-RERE | 20 (40 μL) | 200 μL |
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| SLC37A1-MTA1-20-REOR | 20 (40 μL) | 200 μL |
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| SLC37A1-MTA1-20-REGO | 20 (40 μL) | 200 μL |
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| SLC37A1-MTA1-20-REGR | 20 (40 μL) | 200 μL |
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| SLC37A1-MTA1-20-REAQ | 20 (40 μL) | 200 μL |
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| SLC37A1-MTA1-20-ORRE | 20 (40 μL) | 200 μL |
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| SLC37A1-MTA1-20-OROR | 20 (40 μL) | 200 μL |
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| SLC37A1-MTA1-20-ORGO | 20 (40 μL) | 200 μL |
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| SLC37A1-MTA1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SLC37A1-MTA1-20-GORE | 20 (40 μL) | 200 μL |
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| SLC37A1-MTA1-20-GOOR | 20 (40 μL) | 200 μL |
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| SLC37A1-MTA1-20-GOGO | 20 (40 μL) | 200 μL |
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| SLC37A1-MTA1-20-GOGR | 20 (40 μL) | 200 μL |
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| SLC37A1-MTA1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SLC37A1-MTA1-20-GRRE | 20 (40 μL) | 200 μL |
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| SLC37A1-MTA1-20-GROR | 20 (40 μL) | 200 μL |
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| SLC37A1-MTA1-20-GRGO | 20 (40 μL) | 200 μL |
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| SLC37A1-MTA1-20-GRGR | 20 (40 μL) | 200 μL |
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| SLC37A1-MTA1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SLC37A1-MTA1-20-AQRE | 20 (40 μL) | 200 μL |
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| SLC37A1-MTA1-20-AQOR | 20 (40 μL) | 200 μL |
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| SLC37A1-MTA1-20-AQGO | 20 (40 μL) | 200 μL |
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| SLC37A1-MTA1-20-AQGR | 20 (40 μL) | 200 μL |
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| SLC37A1-MTA1-20-AQAQ | 20 (40 μL) | 200 μL |
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MTA1 Gene Summary
This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
Gene Name: Metastasis Associated 1
Chromosome: CHR14: 105886185 -105937057
Locus: 14q32.33
SLC37A1 Gene Summary
The protein encoded by this gene localizes to the endoplasmic reticulum (ER) membrane. This protein translocates glucose-6-phosphate from the cytoplasm into the lumen of the ER for hydrolysis into glucose by another ER membrane protein. This gene is a member of the solute carrier 37 gene family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Gene Name: Solute Carrier Family 37 Member 1
Chromosome: CHR21: 43919741 -44001550
Locus: 21q22.3
Gene Diseases
The SLC37A1 MTA1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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